Chirurgisches Forum und DGAV Forum 2009
für experimentelle und klinische Forschung 126. Kongress der Deutschen Gesellschaft für Chirurgie München, 28.04.-01.05.2009
Article
Article
Angiogenesis, the formation of new blood vessels from the endothelium of the existing vasculature, describes a crucial process in tumor growth, disease progression, and metastasis. Therefore, the upcoming stra...
Article
Soft tissue sarcomas (STS) are rare tumors. General treatment is difficult while multimodality treatment strategies are more and more common. In these strategies, surgical resection of the primary tumor is ess...
Book and Conference Proceedings
für experimentelle und klinische Forschung 126. Kongress der Deutschen Gesellschaft für Chirurgie München, 28.04.-01.05.2009
Chapter and Conference Paper
Introduction: The influence of tumour associated stromal cells on tumour growth and on the potential to metastasize is already issue of current research [1,2,3]. In preclinical studies of a breas...
Chapter and Conference Paper
The liver is a highly metabolic organ with a great potential of regeneration. Beside mitogenic signals via hepatotrophic growth factors like EGF (epidermal growth factor), HGF (hepatocyte growth factor) and AL...
Chapter and Conference Paper
Background: In the present study, we aimed to identify and to eliminate putative cancer stem cells (CSC) within different human pancreatic cancer cell lines as well as within 5-Fluorouracil-resis...
Chapter and Conference Paper
Background: The endothelial receptors that control leukocyte transmigration in the postischemic liver are not identified. This study was designed to investigate the role of endothelial cell selec...
Chapter and Conference Paper
Advanced gastrointestinal tumors have a poor prognosis and are largely unresponsive to currently available chemotherapeutic drugs. The development of more effective therapies would be aided by better preclinic...
Chapter and Conference Paper
Health care is facing efficiency (quality) problems while costs are exploding. Quality management (QM) therefore becomes a major strategic challenge. Thus, the international QM system ISO9001:2000 was introduc...
Chapter and Conference Paper
Background: Pancreas carcinoma belongs to one of the most dangerous tumor disease. Therefore it is very important to understand mechanism leading to change of the low angiogenic and low metastati...
Chapter and Conference Paper
Background: We like to prove with this study concept whether intrinsically resistant locally advanced and/or metastatic pancreatic cancer can be treated with a combination of antiangiogenic thera...
Article
Gender-specific immune responses have been found after trauma-hemorrhage. Male and female sex hormones seem to be responsible for this gender dimorphism. Alterations in sex hormone receptor expression in mice ...
Chapter and Conference Paper
Transplantation tolerance is one of the most important issues in organ transplantation. It has previously been shown in murine animal models that pre-treatment of organ recipients with soluble MHC class I (MHC...
Chapter and Conference Paper
Introduction: Modern immunosuppressives have markedly improved graft survival after solid organ transplantation. However, these substances are associated with negative effects on transplant funct...
Book and Conference Proceedings
für experimentelle und klinische Forschung 125. Kongress der Deutschen Gesellschaft für Chirurgie Berlin, 22.04. – 25.04.2008
Chapter and Conference Paper
Background: Augmenter of liver regeneration (ALR) is an endogenous protein, which shows increased expression after liver resection but that also acts as a liver specific growth factor. In vitro s...
Chapter and Conference Paper
Background: Despite significant advances in conventional therapeutic approaches, the five-year overall survival rate of CRC patients with an intended curative resection (R0) is less than 50 %. Th...
Chapter and Conference Paper
Background: The contribution of cancer stem cells (CSC) to pancreatic cancer has not been established yet. Furthermore, the presence of cancer stem cells in chemotherapy-resistant pancreatic canc...
Chapter and Conference Paper
Introduction: The major histocompatibility complex class I related A (MICA) and MICB molecules are ligands of NKG2D receptors on gamma/delta natural killer cells and CD8aß T cells and mediate hos...