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  1. Article

    Open Access

    ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

    The mechanisms of initiation of pancreatic ductal adenocarcinoma (PDAC) are still largely unknown. In the present study, we analysed the role of anterior gradient-2 (AGR2) in the earliest stages of pancreatic ...

    L Dumartin, W Alrawashdeh, S M Trabulo, T P Radon, K Steiger, R M Feakins… in Oncogene (2017)

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  2. No Access

    Chapter and Conference Paper

    Cell-based therapy using endothelial progenitor cells rescues kidney from ischemia-reperfusion injury

    In the past years, optimization of immunosuppressive protocols considerably reduced the incidence of acute rejection after kidney transplantation. In contrast, very little progress has been achieved in the fie...

    Dr. med. T. Herrler, A. Tischer, S. Nowak… in Chirurgisches Forum und DGAV Forum 2009 (2009)

  3. No Access

    Chapter and Conference Paper

    Einsatz muriner mesenchymaler Stammzellen zur Expression spenderspezifischer MHC Klasse I Moleküle zur spenderspezifischen Immunsuppression in der allogenen Organtransplantation

    Transplantation tolerance is one of the most important issues in organ transplantation. It has previously been shown in murine animal models that pre-treatment of organ recipients with soluble MHC class I (MHC...

    P. Camaj, I. Ischenko, C. Heeschen, K. -W. Jauch… in Chirurgisches Forum 2008 (2008)

  4. No Access

    Chapter and Conference Paper

    Bedeutung der Familien der Src Tyrosinkinasen in der Lymphangiogenese

    Introduction: The close association of lymphatic and blood vessels and their coordinated development in vivo suggest that some molecules may control both hemangiogenesis and lymphangiogenesis. We...

    Dr.med. Ivan Ischenko, S. Huber, M. Guba, C. Heeschen… in Chirurgisches Forum 2007 (2007)

  5. No Access

    Chapter and Conference Paper

    Stammzell-basierte Tie2/Tk Suizidgentherapie des fortgeschrittenen Pankreaskarzinoms

    Introduction: Stem cells and endothelial progenitor cells play an important role in modulating tumour growth. After recruitment of stem cells from different niches, endothelial transdifferentiati...

    Hanno Niess, C. Conrad, R. Huss, I. v. Lüttichau, I. Ischenko… in Chirurgisches Forum 2007 (2007)

  6. No Access

    Chapter and Conference Paper

    Anti-tumorigene und anti-angiogenetische Wirkung des Immunsuppressivums FTY720

    G. Schmid, M. Guba, A. Papyan, I. Ischenko, C. J. Bruns… in Chirurgisches Forum 2006 (2006)

  7. No Access

    Chapter

    Diabetiker und akutes Koronarsyndrom

    C. Heeschen, C. Hamm in Diabetes und Herz (2005)

  8. No Access

    Article

    Beneficial effects of statins in patients with non-ischemic heart failure

    Experimentelle Arbeiten und retrospektive Analysen klinischer Studien lassen einen positiven Effekt von Statinen bei Patienten mit Herzinsuffizienz vermuten. Möglicherweise ist hieran eine direkte Wirkung von ...

    Dr. U. Laufs, S. Wassmann, S. Schackmann, C. Heeschen… in Zeitschrift für Kardiologie (2004)

  9. No Access

    Article

    High background levels compromise the use of cardiac troponin I RNA detection in peripheral blood as a diagnostic tool in cardiology

    The detection of cardiac troponins in peripheral blood as protein markers of myocardial infarction is a new diagnostic tool in the diagnosis of cardiac disease. In order to increase the sensitivity and specifi...

    P. Tschentscher, C. Heeschen, C. Hamm… in International Journal of Clinical and Labo… (2000)

  10. No Access

    Chapter

    Der „Akense Afasietest“ — Erfahrungen und Probleme bei der Validierung

    Der „Akense Afasietest“ wurde erstellt, um über ein vergleichbares Ausleseverfahren für deutsche und niederländische Aphasiker zu verfügen. Dies ist u.a. für sprachlich-kontrastive neurolinguistische Untersuch...

    C. Heeschen, R. de Bleser, P. Graetz… in Neuroimmunologie Spinale Krankheiten Neuro… (1987)

  11. No Access

    Chapter

    Der „Akense Afasietest“ — eine niederländische Fassung des AAT (Aachener Aphasietest)

    R. de Bleser, P. Graetz, P. Hagoort… in Neuroimmunologie Spinale Krankheiten Neuro… (1987)