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  1. Article

    Open Access

    EnGraft: a multicentre, open-label, randomised, two-arm, superiority study protocol to assess bioavailability and practicability of Envarsus® versus Advagraf™ in liver transplant recipients

    Graft rejection and chronic CNI toxicity remain obstacles to organ transplant success. Current formulations of tacrolimus, such as Prograf® and Advagraf™, exhibit limitations in terms of pharmacokinetics and t...

    D. S. Wöhl, B. James, M. Götz, F. Brennfleck, I. Holub-Hayles, I. Mutzbauer in Trials (2023)

  2. Article

    Open Access

    Endoscopic vacuum therapy significantly improves clinical outcomes of anastomotic leakages after 2-stage, 3-stage, and transhiatal esophagectomies

    Anastomotic leakages after esophagectomies continue to constitute significant morbidity and mortality. Intrathoracic anastomoses pose a high risk for mediastinitis, sepsis, and death, if a leak is not addresse...

    Jonas Maier, A. Kandulski, N. E. Donlon, J. M. Werner in Langenbeck's Archives of Surgery (2023)

  3. No Access

    Article

    Reversal of end-ileostomy in patients with Crohn’s disease

    End-ileostomy after two-staged ileocolic resection is frequently performed in Crohn’s disease patients at high risk for postoperative complications. However, there is paucity on data regarding the morbidity af...

    I. Iesalnieks, T. Bittermann, H. J. Schlitt in International Journal of Colorectal Disease (2021)

  4. Article

    Open Access

    Stereotactic Percutaneous Electrochemotherapy as Primary Approach for Unresectable Large HCC at the Hepatic Hilum

    Electrochemotherapy (ECT) is a novel non-thermal ablative technique that combines chemotherapy and the application of electric pulses for reversible cell membrane electroporation. This method was recently perf...

    L. Luerken, M. Doppler, S. M. Brunner in CardioVascular and Interventional Radiology (2021)

  5. Article

    Open Access

    Super selective percutaneous transhepatic coil embolization of intrahepatic pseudoaneurysm after pediatric liver transplantation: a case report

    Intrahepatic arterial pseudoaneurysms are a rare, life-threatening complication after pediatric liver transplantation. Treatment of choice represents interventional radiological management with endovascular em...

    V. I. Huf, D. Grothues, B. Knoppke, H. Goessmann, W. A. Wohlgemuth in CVIR Endovascular (2021)

  6. No Access

    Article

    Intraoperativer Ultraschall in der Viszeralchirurgie

    Der Einsatz des intraoperativen Ultraschalls ist gängige Praxis in der Chirurgie der parenchymatösen Organe. Neben der reinen Möglichkeit, Läsionen zu detektieren, ermöglichen Perfusions- und Elastizitätsanaly...

    PD Dr. C. Hackl, F. Bitterer, N. Platz Batista da Silva, E. M. Jung in Der Chirurg (2020)

  7. No Access

    Article

    Risk of postoperative morbidity in patients having bowel resection for colonic Crohn’s disease

    The aim of the present multicenter study was to analyze the incidence and risk factors associated with postoperative morbidity in patients who had colorectal resection for colonic Crohn’s disease.

    Igors Iesalnieks, A. Spinelli, M. Frasson, F. Di Candido in Techniques in Coloproctology (2018)

  8. Article

    Einfluss sozialer Charakteristika auf die Behandlungsdauer, Erkrankungsschwere und soziale Unterstützung von Patienten einer operativen Intensivstation

    Ein niedriger sozioökonomischer Status (SES) ist bei schweren Erkrankungen mit einer höheren Morbidität und Mortalität assoziiert. Ob neben dem SES weitere individuelle Faktoren (Geschlecht, Versichertenstatus...

    Dr. S. Blecha, H. J. Schlitt, B. M. Graf, M. Leitzmann, T. Bein in Der Anaesthesist (2018)

  9. No Access

    Chapter

    Treatment of Peritoneal Carcinomatosis

    Peritoneal carcinomatosis is defined as a metastatic spread of a malignant tumor into the peritoneal cavity. Previously, patients suffering from this kind of malignant peritoneal dissemination were supposed to...

    M. Hornung, H. J. Schlitt in Locoregional Tumor Therapy (2018)

  10. No Access

    Article

    Preservation of the superior rectal artery: influence of surgical technique on anastomotic healing and postoperative morbidity in laparoscopic sigmoidectomy for diverticular disease

    To evaluate the impact of superior rectal artery (SRA) sparing technique on anastomotic leakage in laparoscopic sigmoidectomy for diverticular disease.

    Maximilian Sohn, H. J. Schlitt, M. Hornung in International Journal of Colorectal Disease (2017)

  11. No Access

    Article

    Evaluation of a robotic system for irreversible electroporation (IRE) of malignant liver tumors: initial results

    Comparison of conventional CT-guided manual irreversible electroporation (IRE) of malignant liver tumors and a robot-assisted approach regarding procedural accuracy, intervention time, dose, complications, and...

    L. P. Beyer, B. Pregler, K. Michalik in International Journal of Computer Assisted… (2017)

  12. No Access

    Article

    Extrakorporale CO2-Elimination als Alternative zur Tracheotomie bei Weaningversagen

    Wir berichten über einen Patienten mit Thoraxtrauma, der nach operativer Versorgung auf die Intensivstation aufgenommen wurde. Nach Erfüllung entsprechender Protokollkriterien wurde er am 7. postoperativen Tag...

    Priv.-Doz. Dr. med. A. Redel MHBA, M. Ritzka, S. Kraus, A. Philipp in Der Anaesthesist (2016)

  13. No Access

    Article

    CRS-HIPEC Prolongs Survival but is Not Curative for Patients with Peritoneal Carcinomatosis of Gastric Cancer

    Peritoneal carcinomatosis (PC) is a dismal feature of gastric cancer that most often is treated by systemic palliative chemotherapy. In this retrospective matched pairs-analysis, we sought to establish whether...

    T. Boerner, A. Graichen, T. Jeiter, F. Zemann, P. Renner in Annals of Surgical Oncology (2016)

  14. No Access

    Article

    Die Herausforderung akute Nierenschädigung

    Die akute Nierenschädigung [„acute kidney injury“ (AKI)] stellt eine häufige und schwerwiegende Komplikation bei kritisch kranken Patienten dar. Aktuelle Daten zur Prävalenz und den resultierenden Kosten der A...

    Dr. I. Göcze, T. Bergler, E. Bossauer in Medizinische Klinik - Intensivmedizin und … (2016)

  15. No Access

    Article

    Robot-assisted microwave thermoablation of liver tumors: a single-center experience

    To evaluate and compare the needle placement accuracy, patient dose, procedural time, complication rate and ablation success of microwave thermoablation using a novel robotic guidance approach and a manual app...

    L. P. Beyer, B. Pregler, C. Niessen in International Journal of Computer Assisted… (2016)

  16. No Access

    Article

    Gallefisteln und biliäre Stauung nach hepatopankreatobiliären Eingriffen

    Biliäre Komplikationen nach hepatopankreatobiliären Eingriffen können schwerwiegende Folgen für die langfristige Lebensqualität unserer Patienten haben. Die adäquate und zeitgerechte Diagnose des vorliegenden ...

    Prof. Dr. M.-H. Dahlke Ph.D, M. Loss, H.J. Schlitt in Der Chirurg (2015)

  17. No Access

    Article

    „Pit-picking“-Operation bei Patienten mit Sinus pilonidalis

    Minimal-invasive Operationen für die Behandlung des Sinus pilonidalis gewinnen eine zunehmende Verbreitung, allerdings sind die mittel- und die langfristigen Ergebnisse noch unzureichend erforscht.

    PD Dr. I. Iesalnieks, S. Deimel, H.J. Schlitt in Der Chirurg (2015)

  18. Article

    Open Access

    mTOR inhibition improves fibroblast growth factor receptor targeting in hepatocellular carcinoma

    Systemic therapy has proven only marginal effects in hepatocellular carcinoma (HCC) so far. The aim of this study was to evaluate the effect of targeting fibroblast growth factor receptor (FGFR) on tumour and ...

    T Scheller, C Hellerbrand, C Moser, K Schmidt, A Kroemer in British Journal of Cancer (2015)

  19. Article

    Contrast-enhanced ultrasonography for bedside imaging in subclinical acute kidney injury

    I. Göcze, W. A. Wohlgemuth, H. J. Schlitt, E. M. Jung in Intensive Care Medicine (2014)

  20. No Access

    Article

    Localizzazione altamente efficiente delle ghiandole patologiche nell’iperparatiroidismo primitivo mediante l’uso dell’ecografia con contrasto rispetto all’ultrasonografia convenzionale

    A. Agha, M. Hornung, C. Stroszczynski, H. J. Schlitt, E. M. Jung in L’Endocrinologo (2013)

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