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Article
Correction: Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells
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Article
Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells
Resistance to apoptosis, for example due to overexpression of Inhibitor of Apoptosis (IAP) proteins, is associated with poor prognosis in acute myeloid leukemia (AML). Here, we identify that Smac mimetics such...
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Article
ENT-specific therapy of obstructive sleep apnoea in adults
The German Society of Otorhinolaryngology, Head and Neck Surgery recently has released the abbreviated version of its scientific guideline “ENT-specific therapy of obstructive sleep apnoea (OSA) in adults”, wh...
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Article
Abstracts
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Article
Ultrastructure of the terminal globule of the oncomiracidium of Zeuxapta seriolae (Meserve, 1938) (Monogenea, Polyopisthocotylea, Axinidae)
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Article
Deletion map** and linkage analysis provide strong indication for the involvement of the human chromosome region 8p12-p22 in breast carcinogenesis
We have identified a high frequency of loss of heterozygosity (LOH) on the human chromosome region 8p12-p22 in a panel of microdissected familial (86% LOH) and sporadic (74% LOH) breast tumours. The two most f...
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Article
Relationship of polymorphisms in the renin-angiotensin system and in E-selectin of patients with early severe coronary heart disease
Previous association studies between angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) polymorphisms and several cardiovascular diseases have reported variable results. Therefore we examined the a...
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Article
Aspects of the phylogeny of Platyhelminthes based on 18S ribosomal DNA and protonephridial ultrastructure
DNA studies of 23 taxa (20 platyhelminths, 1 nemertean, Homo and Artemia) and electron-microscopic studies of the protonephridia of many platyhelminths (supported by some additional ultrastructural data) have led...
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Article
Ultrastructure of spermiogenesis and spermatozoa ofNeopolystoma spratti (Platyhelminthes, Monogenea, Polystomatidae)
Spermiogenesis inNeopolystoma spratti conforms to the basic pattern found in polyopisthocotylean monogeneans and in Trematoda Digenea and Trematoda Aspidogastrea. The zone of differentiation exhibits a complete r...
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Chapter and Conference Paper
Aspects of the phylogeny of Platyhelminthes based on 18S ribosomal DNA and protonephridial ultrastructure
DNA studies of 23 taxa (20 platyhelminths, 1 nemertean, Homo and Artemia) and electron-microscopic studies of the protonephridia of many platyhelminths (supported by some additional ultrastructural data) have led...
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Article
Two new sensory receptors inGyrodactylus sp. (Platyhelminthes, Monogenea, Monopisthocotylea)
Two pairs of sub-surface ciliary aggregations, not previously described in gyrodactylid monogeneans, have been found in the antero-dorsal region of adultGyrodactylus sp. One pair lies more anteriorly and has seve...
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Article
Ultrastructure of sperm and spermiogenesis ofPterastericola astropectinis (Platyhelminthes, Rhabdocoela, Pterastericolidae)
During development of the spermatid, two free flagella are transported distally from the main spermatid mass by elongation of the shaft. They rotate back towards the shaft and lie parallel with it prior to fus...
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Article
Ultrastructure of the protonephridial system of regenerating Stenostomum sp. (Plathelminthes, Catenulida)
The ultrastructure of the flame bulbs, protonephridial capillaries and duct of fully developed and regenerating Stenostomum sp. is described. Flame bulbs are formed by a single cell whose nucleus is located basal...
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Article
Ultrastructure of sperm and spermatogenesis ofRugogaster hydrolagi, Schell 1973 (Platyhelminthes, Trematoda, Aspidogastrea, Rugogastridae)
Mature sperm ofRugogaster hydrolagi exhibit the structure typical of Trematoda, with 2 axonemes of the 9+“1” pattern being incorporated into the sperm body, dorsal and ventral microtubules occurring in the princi...
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Article
Ultrastructure of the develo** protonephridial system of the cercaria ofPhilophthalmus sp. (Trematoda, Digenea)
The fully developed flame bulb ofPhilopthalmus exhibits the structure characteristic of Trematoda and Monogenea: external and internal ribs forming a weir, external and internal leptotriches, and two longitudinal...
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Article
Calicotyle australiensis n. sp. and Calicotyle sp. (Monogenea, Monopisthocotylea) from the rectum and rectal glands, and Rugogaster hydrolagi Schell, 1973 (Trematoda, Aspidogastrea) from the rectal glands of holocephalans off the coast of southeastern Australia
Calicotyle australiensis n. sp. from Chimaera sp., caught off the coast of New South Wales, is described. It differs from the other species of the genus in the combination of the following characteristics: lengt...
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Article
Ultrastructure of spermatogenesis and sperm ofMulticotyle purvisi (Plathelminthes, Aspidogastrea)
The ultrastructure of spermatogenesis is described for the first time in an aspidogastrean. The zone of differentiation which is usually formed during digenean spermiogenesis was not observed inMulticotyle purvis...
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Article
Secondary sensory receptor in a platyhelminth
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Article
Ultrastructure of pigmented photoreceptors of larvalMulticotyle purvisi (Trematoda, Aspidogastrea)
The two eyespots of larvalMulticotyle purvisi lie on the posterior of the brain dorsal to the pharynx. Each ocellus consists of one pigment cell and two rhabdomeres, one in the antero-lateral and one in the poste...
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Article
Non-ciliate sensory receptors of larvalMulticotyle purvisi (Trematoda, Aspidogastrea)
Four types of presumptive non-ciliate sensory receptors of larvalMulticotyle purvisi (Trematoda, Aspidogastrea) are described by transmission electronmicroscopy. One pair of receptors in the mouth cavity has two ...