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Article
The impact of online yoga on sleep and quality of life in women with breast cancer: a randomized trial
There is growing evidence of the benefit of physical activity and mindfulness in breast cancer patients (HC et al. in BMC Complement Altern Med, 2017). Yoga offers a combination of both. The aim of this study ...
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Article
Open AccessCorrection to: Use of oral contraceptives in BRCA mutation carriers and risk for ovarian and breast cancer: a systematic review
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Article
Open AccessImplant-based immediate reconstruction in prophylactic mastectomy: is the caudal dermis flap a reliable alternative to synthetic mesh or acellular dermal matrix?
The demand for prophylactic mastectomy has increased significantly over the last 10 years. This can be explained by a substantial gain of knowledge about the clinical risk and outcome of patients with high ris...
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Article
Open AccessHormone replacement therapy in BRCA mutation carriers and risk of ovarian, endometrial, and breast cancer: a systematic review
BRCA mutation carriers have an increased risk of develo** breast or ovarian cancer. Risk-reducing bilateral sal**o-oophorectomy (RRBSO) is associated with a decrease in risk for tubal and ovarian cancer. Horm...
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Article
Open AccessUse of fertility treatments in BRCA1/2 mutation carriers and risk for ovarian and breast cancer: a systematic review
Mutations in the genes BRCA1 and BRCA2 represent a significant risk factor for ovarian and breast cancer. With increasing number and success rates, fertility protection and treatment are gaining importance also f...
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Article
Management der frühen rheumatoiden Arthritis
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Article
Open AccessUse of oral contraceptives in BRCA mutation carriers and risk for ovarian and breast cancer: a systematic review
BRCA mutation carriers have an increased risk of develo** breast or ovarian cancer. Oral contraception (OC) is known to increase breast cancer and reduce ovarian cancer risk in the general population. This revi...
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Article
The impact of a cervical dysplasia diagnosis on individual cancer prevention habits over time: a bicentric case–control study
Annual cervical cancer screening is recommended in Germany as a part of the statutory preventive care. Abnormal results can provoke psychological distress and anxiety, compromising women’s adherence. Little is...
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Article
S2e-Leitlinie: Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten
Medikamentöse Therapiestrategien zur Behandlung der rheumatoiden Arthritis sind entscheidend für den Langzeitverlauf. Sie dienen dem Ziel, durch frühe und konsequente Unterdrückung der Entzündung Gelenkzerstör...
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Article
Ein riesiger Mammatumor – nicht immer ein Mammakarzinom
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Article
Receptors for luteinizing hormone-releasing hormone (GnRH) as therapeutic targets in triple negative breast cancers (TNBC)
Triple negative breast cancers express receptors for gonadotropin-releasing hormone (GnRH) in more than 50 % of the cases, which can be targeted with peptidic analogs of GnRH, such as triptorelin. The current ...
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Article
Risikokommunikation bei operativen Eingriffen am Beispiel der Hysterektomie
Ein zentrales Thema im Arzt-Patienten-Gespräch sind Risiken. Die verständliche Vermittlung von statistischen Daten, u. a. zu Häufigkeiten (un)erwünschter Ereignisse soll den Entscheidungsprozess für bzw. gegen...
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Article
Therapierefraktäre Monarthritis des Handgelenks unter TNF-α-Blockade
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Article
Silikonabriebassoziierte Dupuytren-Kontraktur bei Spätversagen einer Lunatumspacerprothese
Die Pathophysiologie der palmaren Fibromatose (Morbus Dupuytren) ist bis heute nicht vollständig verstanden. In den meisten Fällen jedoch können reaktive und reparative Prozesse des sehnenartigen Gewebes klini...
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Article
Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis
Indolent systemic mastocytosis (ISM) can trigger bone loss. However, the clinical relevance of different mast cell infiltration patterns for bone remains to be clarified. Here, we report increased bone turnove...
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Article
Impaired bone mineralization accompanied by low vitamin D and secondary hyperparathyroidism in patients with femoral neck fracture
Although it is well established that a decrease in bone mass increases the risk of osteoporotic fractures, the proportion of fractures attributable to areal bone mineral density (BMD) is rather low. Here, we h...
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Article
Targeted chemotherapy of endometrial, ovarian and breast cancers with cytotoxic analogs of luteinizing hormone-releasing hormone (LHRH)
Receptors luteinizing hormone-releasing hormone (LHRH) are expressed in about 80 % of human endometrial and ovarian cancers and account for more than 50 % of breast cancers including triple negative breast can...
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Article
Vaginal estrogen therapy in postmenopausal breast cancer patients treated with aromatase inhibitors
Breast cancer is the most frequent cancer among women with about 1.38 million new cases worldwide every year. Most of these patients are postmenopausal and suffer from hormone receptor positive breast tumors. ...
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Article
Vaginale Östrogentherapie bei Mammakarzinompatientinnen
Die Mehrzahl der Mammakarzinompatientinnen befindet sich zum Zeitpunkt der Erstdiagnose in der Postmenopause. Neben vasomotorischen Beschwerden wie Hitzewallungen und Schweißausbrüchen leidet eine Vielzahl der...
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Article
Skeletal mineralization defects in adult hypophosphatasia—a clinical and histological analysis
Histomorphometry and quantitative backscattered electron microscopy of iliac crest biopsies from patients with adult hypophosphatasia not only confirmed the expected enrichment of non-mineralized osteoid, but ...
