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  1. No Access

    Article

    Is aryl hydrocarbon hydroxylase activity a new prognostic indicator for breast cancer?

    Aryl hydrocarbon hydroxylase (AHH) activity was measured in the breast tumours of 153 primary and 17 recurrent cancer patients, and in 18 patients with benign breast tumour. All operations were carried out in ...

    K Pyykkö, R Tuimala, L Aalto, T Perkiö in British Journal of Cancer (1991)

  2. No Access

    Article

    The relationship between debrisoquine oxidation phenotype and the pharmacokinetics of chlorpropamide

    The pharmacokinetics and urinary metabolite pattern of a single oral dose of chlorpropamide 250 mg have been studied in 6 extensive and 5 poor metabolizers of debrisoquine. Ammonium chloride was given orally t...

    J. Kallio MD, R. Huupponen, K. Pyykkö in European Journal of Clinical Pharmacology (1990)

  3. No Access

    Chapter and Conference Paper

    Inhibition of Microsomal Monooxygenases in Vitro by Aromatic Hydrocarbons

    The effect of benzene, toluene, di- and trimethyl-, ethyl- and propylbenzenes, and styrene on the in vitro activity of rat liver microsomal aryl hydrocarbon hydroxylase and 7-ethoxycoumarin O-deethylase were d...

    K. Pyykkö in Toxic Interfaces of Neurones, Smoke and Genes (1986)

  4. No Access

    Article

    Chronic occupational exposure to toluene

    Chronic occupational exposure to toluene was studied in a factory preparing tarpaulins. Seventy-eight workers were studied; 46 were exposed to various concentrations of toluene in air (20–200 ppm), 32 were une...

    H. Tähti, S. Kärkkäinen, K. Pyykkö… in International Archives of Occupational and… (1981)