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Adult Versus Paediatric Craniopharyngiomas: Which Differences?
Despite some apparent similarities several differences exist between adult and paediatric craniopharyngiomas starting from the histology. Papillary CPs occur almost exclusively in adults, whereas adamantinomat...
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Article
Re-Appraisal of Estrogen Receptor Negative/Progesterone Receptor Positive (ER−/PR+) Breast Cancer Phenotype: True Subtype or Technical Artefact?
Expression of the ER and PR receptors is routinely quantified in breast cancer as a predictive marker of response to hormonal therapy. Accurate determination of ER and PR status is critical to the optimal sele...
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Article
Open AccessBritish Society of Breast Radiology Annual Scientific Meeting 2016
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Article
A qualitative analysis of the attitudes of Irish patients towards participation in genetic-based research
Progress in diagnostic and therapeutic strategies in medicine is dependent upon high-quality biomedical research. Technological advances have facilitated improved understanding of disease aetiology, and rapidl...
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Article
Analysis of subsequent publication and impact of abstracts presented at the Sir Peter Freyer Surgical Symposium: Focus on the Plenary Session
The quality of abstracts presented at a conference reflects the academic activity and research productivity of the surgical/scientific association concerned. The abstract to publication rate (44.5 % internatio...
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Article
Familial breast cancer genetic testing in the West of Ireland
The majority of hereditary breast and ovarian cancers are associated with highly penetrant mutations in two genes: BRCA 1 and 2. Our aim was to investigate the prevalence and types of BRCA mutations in patient...
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Article
Intracystic papillary carcinoma of the male breast: a case report and review of the literature
Carcinoma of the male breast is an infrequent and poorly understood disease (Sinha et al. in Ann R Coll Surg Engl 88(5):W3–W5, 2006). It differs from female breast cancer in both demographic and histopathologi...
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Article
Open AccessA call for collaboration in surgical oncology
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Article
The h index and the identification of global benchmarks for breast cancer research output
The h index is used to assess an individual’s contribution to the literature. This metric should not be employed to compare individuals across research areas; rather each subject should have its own baseline and ...
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Article
A study of pre-operative type and screen in breast surgery: improved efficiency and cost saving
Patients undergoing major breast surgery have an almost negligible need for blood transfusions. However, type and screen requests are still routinely performed. This represents an inefficient utilization of re...
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Article
Surgical management of perforated peptic ulcer disease
Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world.The role of postoperative empiric Helicobacter Pylori eradication therapy is controve...
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Article
Radioablation therapy is an essential adjunct to ensure total thyroidectomy for carcinoma
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Article
Determining validity and knowledge transfer efficiency for a novel entirely web based lecture series
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Article
Minimally invasive parathyroidectomy with operative ultrasound localization of the adenoma
Minimally invasive parathyroidectomy is the procedure of choice for primary hyperparathyroidism due to parathyroid adenoma. Adequate perioperative adenoma localization is essential for this operation. We descr...
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Article
Changing trends in the management of gallstone disease
Background: Day case cholecystectomy is increasingly becoming a management option for elective cases while “same admission” cholecystectomy is now considered a favorable option in the tre...
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Article
Multimodal therapy results in systemic T-cell activation and heightened T-cell response to surgery
Neo-adjuvant therapy results in phenotypic evidence of T-cell priming and activation, theoretically heightening the consequences of a ‘second hit’ in the post-operative period and increasing the risk of peri-o...
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Article
Laparoscopic appenclicectomy: we can learn if!
These results confirm that laparoscopic appendectomy is a rapidly acquired skill that can be introduced at any level of surgical training. Time-to-train should not preclude institutions from considering adopti...
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Article
The Fas counter-attack: a role in the systemic inflammatory response syndrome?
These results confirm that surgery primes the immune system for a proinflammatory response to bacterial superantigen. However, this data does not support the concept that Fas ‘counter-attack’ is involved and i...
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Article
Is the laparoscopic approach appropriate for appendicitis? An audit of 391 consecutive cases
We would advocate a policy of laparoscopy for all suspected cases of acute appendicitis. Hospital stay and complication rates following CA are similar to that of OA. Additionally, open surgery mandates appendi...
