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  1. No Access

    Article

    Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways

    Loss of tumour suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES), and genome-wide analyses have revealed...

    A R Dallosso, B Øster, A Greenhough, K Thorsen, T J Curry, C Owen, A L Hancock… in Oncogene (2012)

  2. No Access

    Article

    Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes

    Aberrant activation of the Wnt signaling pathway is causally involved in the formation of most colorectal cancers (CRCs). Although detailed knowledge exists regarding Wnt-regulated protein-coding genes, much l...

    T Schepeler, A Holm, P Halvey, I Nordentoft, P Lamy, E M Riising… in Oncogene (2012)

  3. No Access

    Article

    A 3-Year Longitudinal Study of the Effect of Physical Activity on the Accrual of Bone Mineral Density in Healthy Adolescent Males

    It has previously been suggested that physical activity predominantly influences the accumulation of bone density before puberty. The purpose of the present study was to examine the effect of physical activity...

    A. Gustavsson, K. Thorsen, P. Nordström in Calcified Tissue International (2003)

  4. No Access

    Article

    Effects of moderate endurance exercise on calcium, parathyroid hormone, and markers of bone metabolism in young women

    We investigated the short-term (1 hour-3 days) effects of a 45 minute run on calcium, parathyroid hormone, the carboxyterminal propeptide of type I procollagen (PICP), and the immunoactive carboxyterminal telo...

    K. Thorsen, A. Kristoffersson, J. Hultdin, R. Lorentzon in Calcified Tissue International (1997)

  5. No Access

    Article

    Local bone mineral density, muscle strength, and exercise in adolescent boys: A comparative study of two groups with different muscle strength and exercise levels

    The primary objective of the present study was to evaluate the impact of physical activity and muscle strength on bone mineral density (BMD) of the tuberositas tibiac in adolescent boys. Two groups with differ...

    P. Nordström, G. Nordström, K. Thorsen, R. Lorentzon in Calcified Tissue International (1996)

  6. No Access

    Article

    The effects of brisk walking on markers of bone and calcium metabolism in postmenopausal women

    Weight-bearing exercise has been shown to maintain or increase bone mass in younger as well as older individuals but the mechanisms by which mechanical loading affects bone metabolism are not known in detail. ...

    K. Thorsen, A. Kristoffersson, R. Lorentzon in Calcified Tissue International (1996)