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Article
Discriminant function analysis as decision support system for the diagnosis of acute leukemia with a minimal four color screening panel and multiparameter flow cytometry immunophenoty**
Despite several recommendations for standardization of multiparameter flow cytometry (MFC) the number, specificity and combinations of reagents used by diagnostic laboratories for the diagnosis and classificat...
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Article
Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study
To assess the efficacy of an original DAC-7 regimen: daunorubicine (DNR) 60 mg/m2/day, days 1–3; cytarabine (AraC) 200 mg/m2/day, days 1–7; cladribine (2-CdA) 5 mg/m2/day, days 1–5, 400 untreated adult acute myel...
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Article
Selection of rice for iron toxicity tolerance through irradiated caryopsis culture
A protocol for plant regeneration from caryopses of Indica rice via a callus phase was developed and adopted to select regenerants in media simulating iron toxicity. Caryopses of three commercial Sri Lankan rice ...
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Chapter and Conference Paper
Efficacy of an Original Cell Kinetics Based Chemotherapy Regimen Using rHU GM-CSF for Induction and Consolidation Treatment of ALL. Preliminary Analysis
The use of intensive chemotherapy regimens has led to considerable improvement in the prognosis of adult acute lymphoblastic leukemia (ALL), but the results are still unsatisfactory with only about 30% of pati...
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Chapter and Conference Paper
Diagnostic and Prognostic Value of Immunological Leukemia Phenoty**
Unique, monoclonal antibody (MoAb) defined cell differentiation antigens are increasingly accepted as markers for certain cell lines and for particular differentiation stages [1,2]. However, while we clearly d...
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Chapter and Conference Paper
Myelomonocyte Differentiation Antigens in the Diagnosis of Acute Nonlymphocytic Leukemia: the Relevance of CDw65 Antigen as a Screening Marker and the Prognostic Significance of CD15 Expression
Immunological phenoty** of acute lymphoblastic leukemia (ALL) correlates with clinical findings and has contributed to the understanding of the pathophysiology of lymphoid malignancies. On the contrary, the ...
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Chapter and Conference Paper
Expression of CD-15 Antigen on Leukemic Cells — A New Prognostic Factor for Ability to Achieve Complete Remission and for Survival in ANLL
One of the key problems in acute leukemia is the optimal treatment based on adjusted management while at the same time taking into consideration the risk factors [1]. The monoclonal antibodies (MoAbs) directed...