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Article
Open AccessVenous resection increases risk of chyle leak after total pancreatectomy for pancreatic tumors
Existing research on chyle leak (CL) after pancreatic surgery is mostly focused on pancreaticoduodenectomy and lacks investigation on total pancreatectomy (TP). This study aimed to explore potential risk facto...
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Article
Open AccessDevelopment of a Serum-Based MicroRNA Signature for Early Detection of Pancreatic Cancer: A Multicenter Cohort Study
A grim prognosis of pancreatic cancer (PCa) was attributed to the difficulty in early diagnosis of the disease.
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Article
Open AccessCyst fluid glycoproteins accurately distinguishing malignancies of pancreatic cystic neoplasm
Pancreatic cystic neoplasms (PCNs) are recognized as precursor lesions of pancreatic cancer, with a marked increase in prevalence. Early detection of malignant PCNs is crucial for improving prognosis; however,...
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Chapter
Protective Effect of Insole on Foot Injury
Foot injuries such as fractures, ligaments tear, ankle instability often occur often occurred in sports and work. This chapter described protective issues from the perspective of the objective data in the cont...
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Article
A randomised, multicentre trial of somatostatin to prevent clinically relevant postoperative pancreatic fistula in intermediate-risk patients after pancreaticoduodenectomy
Prophylactic somatostatin to reduce the incidence of clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy remains controversial. We assessed the preventive efficacy of somatostati...
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Article
Comparison of minimal invasive versus open radical antegrade modular pancreatosplenectomy (RAMPS) for pancreatic ductal adenocarcinoma: a single center retrospective study
Radical antegrade modular pancreatosplenectomy (RAMPS) was proposed a decade ago with the aim to achieve higher R0 tangential margin and radical N1 lymph node resection for left-sided pancreatic adenocarcinoma...
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Article
Radical antegrade modular pancreatosplenectomy (RAMPS) versus conventional distal pancreatosplenectomy (CDPS) for left-sided pancreatic ductal adenocarcinoma
The insufficient clearance of regional lymph nodes and unsatisfactory R0 resection rate may result in the metastasis of left-sided pancreatic ductal adenocarcinoma (PDAC) after conventional distal pancreatospl...
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Article
Changes in Serum Lactate Level Predict Postoperative Intra-Abdominal Infection After Pancreatic Resection
Postoperative intra-abdominal infection is one of the most serious complications after pancreatic resection. In this article, we investigated the relationship between serum lactate level and postoperative infe...
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Article
Open AccessMetformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation
Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis due to limited therapeutic options. This study examines the roles of genome-wide association study identified PDAC-associated genes as therapeutic tar...
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Chapter
Biomechanical Modeling and Simulation of Lower Limb
The hip joint is important for maintaining body balance. It consists of the pelvic acetabulum and femoral head, surrounded by large and strong muscles, the main function of the hip joint is to bear the load of...
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Article
Open AccessResearch progress on long non-coding RNAs and their roles as potential biomarkers for diagnosis and prognosis in pancreatic cancer
Pancreatic cancer is one of the main causes of tumor-related deaths worldwide because of its low morbidity but extremely high mortality, and is therefore colloquially known as the “king of cancer.” Sudden onse...
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Article
Combined blockade of TGf-β1 and GM-CSF improves chemotherapeutic effects for pancreatic cancer by modulating tumor microenvironment
The interactions between tumor immune microenvironment (TIME) and pancreatic cancer cells can affect chemotherapeutic efficacy; however, the mechanisms still remain largely unknown. Thirty items in TIME were c...
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Article
Open AccessUSP4 function and multifaceted roles in cancer: a possible and potential therapeutic target
Cancer remains one of the major culprits causing disease-related deaths and leads to a high morbidity and similar mortality. Insidious onset, difficult early detection and a lack of broad-spectrum and effectiv...
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Chapter and Conference Paper
Rolling Element Bearing Fault Diagnosis Based on the Wavelet Packet Transform and Time-Delay Correlation Demodulation Analysis
Considering fault impulse signals of rolling element bearings have the features of periodicity and easily to be immerged by background noise, a novel fault feature extraction method based on the wavelet packet...
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Article
Author Correction: Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer featured with high intra-tumoral heterogeneity and poor prognosis. To comprehensively delineate the PDAC intra-tumoral heter...
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Article
Open AccessTumor size classification of the 8th edition of TNM staging system is superior to that of the 7th edition in predicting the survival outcome of pancreatic cancer patients after radical resection and adjuvant chemotherapy
The 8th edition of TNM staging system has been released and it incorporates many changes to the T and N classifications for pancreatic cancer. Comparative study between the 7th and 8th edition of TNM staging syst...
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Article
Preparation and one-step activation of nanoporous ultrafine carbon fibers derived from polyacrylonitrile/cellulose blend for used as supercapacitor electrode
In this work, nanoporous ultrafine carbon fibers have been fabricated by one-step activation of electrospun polyacrylonitrile (PAN)/cellulose acetate (CA) ultrafine fiber using ZnCl2 as an activation agent. CA, a...
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Article
Open AccessPD-L1 in pancreatic ductal adenocarcinoma: a retrospective analysis of 373 Chinese patients using an in vitro diagnostic assay
Programmed death ligand 1 (PD-L1) has shown potential as a therapeutic target in numerous solid tumors. Its prognostic significance has also been established in pancreatic ductal adenocarcinoma (PDAC). The pre...
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Article
Pancreatic cancer — Laparoscopic resection
To assess current role of laparoscopic resection for pancreatic cancer, so as to improve the surgical management of pancreatic cancer.