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Article
Open AccessCirculating eNAMPT as a biomarker in the critically ill: acute pancreatitis, sepsis, trauma, and acute respiratory distress syndrome
Nicotinamide phosphoribosyltransferase (NAMPT) exhibits dual functionality – as an intracellular enzyme regulating nicotinamide adenine dinucleotide metabolism and as an extracellular secreted protein (eNAMPT)...
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Open AccessDevelopment of a biomarker mortality risk model in acute respiratory distress syndrome
There is a compelling unmet medical need for biomarker-based models to risk-stratify patients with acute respiratory distress syndrome. Effective stratification would optimize participant selection for clinica...
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Article
Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice
The preference for and reaction to novelty are strongly associated with addiction to cocaine and other drugs. However, the genetic variants and molecular mechanisms underlying these phenomena remain largely un...
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Article
Open AccessStatistical Inference Methods for Sparse Biological Time Series Data
Comparing metabolic profiles under different biological perturbations has become a powerful approach to investigating the functioning of cells. The profiles can be taken as single snapshots of a system, but mo...
