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  1. No Access

    Article

    Laurén et al. reply

    Replying to: H. W. Kessels, L. N. Nguyen, S. Nabavi & R. Malinow Nature 466, 10.1038/nature09217 (2010)

    Juha Laurén, David A. Gimbel, Haakon B. Nygaard, John W. Gilbert… in Nature (2010)

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    Article

    Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

    The hypothesis that soluble amyloid-β peptide oligomer plays a central role in Alzheimer's disease is well established, yet no mechanistic basis for Aβ oligomer effects on neurons has been described. Several l...

    Juha Laurén, David A. Gimbel, Haakon B. Nygaard, John W. Gilbert… in Nature (2009)

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    Article

    Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

    The drugs currently available for Parkinson's disease patients generally treat only the symptoms, and do not prevent the degeneration and death of dopaminergic neurons in the brain, the cause the motor defects...

    Päivi Lindholm, Merja H. Voutilainen, Juha Laurén, Johan Peränen… in Nature (2007)