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Article
Open AccessLong-term continuous monitoring of arrhythmias in pigs with insertable cardiac monitors
Arrhythmia detection is essential when assessing the safety of novel drugs and therapies in preclinical studies. Many short-term arrhythmia monitoring methods exist, including non-invasive ECG and Holter. Howe...
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Article
Open AccessCardiac vein retroinjections provide an efficient approach for global left ventricular gene transfer with adenovirus and adeno-associated virus
Heart failure (HF) is a major burden worldwide, and new therapies are urgently needed. Gene therapy is a promising new approach to treat myocardial diseases. However, current cardiac gene delivery methods for ...
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Article
Open AccessSpeckle-tracking echocardiography for predicting improvement of myocardial contractile function after revascularization: a meta-analysis of prospective trials
Some studies have indicated that the use of 2D-Speckle tracking echocardiography (2DSTE) aids in predicting recovery of myocardial contractile function after revascularization in patients with chronic ischemic...
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Article
Open AccessObjectively measured preoperative physical activity and sedentary behaviour among Finnish patients scheduled for elective cardiac procedures: baseline results from randomized controlled trial
We investigated preoperative physical activity (PA) and sedentary behaviour (SB) in patients scheduled for elective cardiac procedures and compared them with population-based sample of Finnish adults.
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Article
Open AccessThe nationwide Finnish anticoagulation in atrial fibrillation (FinACAF): study rationale, design, and patient characteristics
Atrial fibrillation (AF) is a major cause of ischemic stroke and the number of AF patients is increasing. Thus, up-to-date multifaceted data about the characteristics of AF patients, their treatments, and outc...
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Article
Open AccessPatient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D
Patient-reported outcome (PRO) instruments measure health gains, including changes in health-related quality of life (HRQoL). Previous studies have assessed the reliability and relationship of multiple HRQoL i...
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Article
Open AccessVernakalant for Rapid Cardioversion of Recent-Onset Atrial Fibrillation: Results from the SPECTRUM Study
Rapid restoration of sinus rhythm using pharmacological cardioversion is commonly indicated in patients with symptomatic recent-onset atrial fibrillation (AF). The objectives of this large, international, mult...
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Article
Open AccessPurchases of medical therapy recommended for coronary artery disease before and after elective revascularisation
We studied the purchases of medical therapy recommended for coronary artery disease patients before and after elective revascularisation (percutaneous coronary intervention (PCI) or coronary bypass grafting (C...
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Article
Response to the letter to the editor by Dr. Yasar and Babaoglu on the recent publication of Kokki et al. on the pharmacokinetics of metoprolol bioavailability in coronary artery bypass surgery patients
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Article
How do different extracorporeal circulation systems affect metoprolol bioavailability in coronary artery bypass surgery patients
Cardiac surgery and conventional extracorporeal circulation (CECC) impair the bioavailability of drugs administered by mouth. It is not known whether miniaturized ECC (MECC) or off-pump surgery (OPCAB) affect ...
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Article
Open AccessAntiarrhythmic drug therapy among patients presenting to emergency department with symptomatic atrial fibrillation – a prospective nationwide cohort
Atrial fibrillation (AF) is a common arrhythmia that causes numerous visits to emergency departments (ED). The aim of the FinFib2 study was to evaluate whether treatment of patients with AF in ED is consistent...
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Article
Open AccessPrediction of ineffective elective cardioversion of atrial fibrillation: a retrospective multi-center patient cohort study
Elective cardioversion (ECV) of atrial fibrillation (AF) is a standard procedure to restore sinus rhythm. However, predictors for ineffective ECV (failure of ECV or recurrence of AF within 30 days) are unknown.
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Article
Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding
No current data are available on rebleeding and mortality risk in patients who use alcohol excessively and are admitted for non-variceal upper gastrointestinal bleeding (NVUGIB). This information could help in...
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Article
Endovascular Therapy as a Primary Revascularization Modality in Acute Mesenteric Ischemia
To evaluate endovascular therapy (EVT) as the primary revascularization method for acute mesenteric ischemia (AMI).
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Article
Response to Kurtoglu and Balta
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Article
Heart rate variability associates with asymptomatic coronary atherosclerosis
Heart rate variability (HRV) becomes impaired in symptomatic coronary artery disease (CAD), particularly, after myocardial infarction. The mechanism how CAD results in impairment of cardiac autonomic regulatio...
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Article
Open AccessComputed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
The prevalence of heart failure (HF) is rising in industrialized and develo** countries. Though invasive coronary angiography (ICA) remains the gold standard for anatomical assessment of coronary artery dise...
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Failure Simulations with a Strain Rate Dependent Ductile-to-Brittle Transition Model
In this paper, simulations with a phenomenological model to describe the ductile-to-brittle transition of rate-dependent solids are presented. The model is based on consistent thermodynamic formulation using p...
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Article
Open AccessDotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
Neointimal formation in atherosclerosis has been subject for intense research. However, good animal models mimicking asymmetrical lesion formation in human subjects have been difficult to establish. The aim of...
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Article
Experimental study on malfunction of pacemakers due to exposure to different external magnetic fields
Cardiac pacemaker malfunction due to exposure to magnetic fields may cause serious problems in some work environments for workers having cardiac pacemakers. The aim of this study was to find the magnetic field...