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Open AccessWeek 240 Efficacy and Safety of Fostemsavir Plus Optimized Background Therapy in Heavily Treatment-Experienced Adults with HIV-1
Efficacy and safety of the attachment inhibitor fostemsavir + optimized background therapy (OBT) were evaluated through 48 and 96 weeks in the phase 3 BRIGHTE trial in heavily treatment-experienced (HTE) adult...
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Article
Open AccessToward Safer Opioid Prescribing in HIV care (TOWER): a mixed-methods, cluster-randomized trial
The 2016 U.S. Centers for Disease Control Opioid Prescribing Guideline (CDC Guideline) is currently being revised amid concern that it may be harmful to people with chronic pain on long-term opioid therapy (CP...
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HIV and Dyslipidemia
With the development of potent and effective antiretroviral therapy (ART), life expectancy for people with HIV (PWH) has increased to the point that HIV is now considered a chronic illness. People with HIV are...
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Article
Convalescent plasma treatment of severe COVID-19: a propensity score–matched control study
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new human disease with few effective treatments1. Convalescent plasma, donated by persons who have...
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Article
An inflammatory cytokine signature predicts COVID-19 severity and survival
Several studies have revealed that the hyper-inflammatory response induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease severity and death. However, predictive bi...
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Article
Atherosclerotic Cardiovascular Disease and Anti-Retroviral Therapy
In the current era of available therapy for human immunodeficiency virus (HIV), life expectancy for persons living with HIV (PLWH) nears that of the general population. Atherosclerotic cardiovascular disease (...
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Article
Soluble Levels of Receptor for Advanced Glycation Endproducts (RAGE) and Progression of Atherosclerosis in Individuals Infected with Human Immunodeficiency Virus: ACTG NWCS 332
Identification of biomarkers and/or mediators of cardiovascular disease (CVD) associated with HIV infection would be of diagnostic and therapeutic value. As soluble receptor for advanced glycation endproducts ...
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Article
HIV Counseling and Testing for Household Members of HIV-Infected Individuals in Africa: Should Prevention Programs Focus on Home-Based Rather than Clinic-Based Outreach?
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Article
New goals for viral suppression in HIV treatment in even the most experienced of patients
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Article
Neuropsychiatric Complications of Antiretroviral Therapy
Neuropsychiatric adverse effects related to potent antiretroviral therapy are among the complications that can lead to poor adherence, treatment interruptions, or change of antiretroviral therapy regimens. For...