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Article
Open AccessNeural signatures of emotion regulation
Emotional experience is central to a fulfilling life. Although exposure to negative experiences is inevitable, an individual’s emotion regulation response may buffer against psychopathology. Identification of ...
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Article
Open AccessDelay discounting and family history of psychopathology in children ages 9–11
Delay discounting is a tendency to devalue delayed rewards compared to immediate rewards. Evidence suggests that steeper delay discounting is associated with psychiatric disorders across diagnostic categories,...
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Structural and Functional Imaging of Alcohol’s Effects on the Brain
Brain imaging has helped reveal acute and chronic effects of alcohol use, and how these effects relate to clinical outcomes in adults with alcohol use disorder (AUD). The prefrontal cortex and the mesocorticol...
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Article
The Neural Circuitry of Reward During Sustained Threat
Reward processing is important for understanding behavior in psychopathology. Opportunities to earn money activate the ventral striatum, as shown by the monetary incentive delay (MID) task. Anxiety conditions ...
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Article
Neuropsychosocial markers of binge drinking in young adults
Binge drinking is associated with disease and death, and develo** tools to identify risky drinkers could mitigate its damage. Brain processes underlie risky drinking, so we examined whether neural and psycho...
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Article
Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies
Endocannabinoid signaling is implicated in an array of psychopathologies ranging from anxiety to psychosis and addiction. In recent years, radiotracers targeting the endocannabinoid system have been used in po...
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Article
Attenuated Insular Processing During Risk Predicts Relapse in Early Abstinent Methamphetamine-Dependent Individuals
There is some evidence that neuroimaging can be used to predict relapse among abstinent methamphetamine-dependent (MD) individuals. However, it remains unclear what cognitive and neural processes contribute to...
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Article
The role of cortisol and psychopathy in the cycle of violence
Child abuse and neglect are universal risk factors for delinquency, violence, and aggression; this phenomenon is known as the cycle of violence. Additional factors—psychopathy, impulsiveness, and disruptions i...
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Article
Zolmitriptan and human aggression: interaction with alcohol
The serotonin 1B/D (5-HT1B/D) receptor has shown potential as a target for decreasing aggression. The 5-HT1B/D agonist zolmitriptan's ability to reduce aggressive behavior in humans and its interaction with the w...
