-
Article
Open AccessNovel methodologies for host-microbe interactions and microbiome-targeted therapeutics in 3D organotypic skin models
Following descriptive studies on skin microbiota in health and disease, mechanistic studies on the interplay between skin and microbes are on the rise, for which experimental models are in great demand. Here, ...
-
Article
Open AccessA generic workflow for Single Locus Sequence Ty** (SLST) design and subspecies characterization of microbiota
We present TaxPhlAn, a new method and bioinformatics pipeline for design and analysis of single-locus sequence ty** (SLST) markers to type and profile bacteria beyond the species-level in a complex microbial...
-
Article
Open AccessImmortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models
The strong societal urge to reduce the use of experimental animals, and the biological differences between rodent and human skin, have led to the development of alternative models for healthy and diseased huma...
