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Article
Open AccessIn-depth proteome analysis of brain tissue from Ewsr1 knockout mouse by multiplexed isobaric tandem mass tag labeling
EWS RNA binding protein 1 (EWSR1) is a multifunctional protein whose epigenetic signatures contribute to the pathogenesis of various human diseases, such as neurodegenerative disorders, skin development, and t...
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Article
Open AccessGene family expansions in Antarctic winged midge as a strategy for adaptation to cold environments
Parochlus steinenii is the only flying insect native to Antarctica. To elucidate the molecular mechanisms underlying its adaptation to cold environments, we conducted comparative genomic analyses of P. steinenii ...
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Article
Open AccessIn-depth blood proteome profiling analysis revealed distinct functional characteristics of plasma proteins between severe and non-severe COVID-19 patients
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over forty million patients worldwide. Although most coronavirus disease 2019 (COVID-19) patients have a good prognosis, some devel...
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Article
Open AccessIdentification of TUBB2A by quantitative proteomic analysis as a novel biomarker for the prediction of distant metastatic breast cancer
Metastasis of breast cancer to distal organs is fatal. However, few studies have identified biomarkers that are associated with distant metastatic breast cancer. Furthermore, the inability of current biomarker...
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Article
Open AccessDeep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease
Alzheimer’s disease (AD), which is the most common type of dementia, is characterized by the deposition of extracellular amyloid plaques. To understand the pathophysiology of the AD brain, the assessment of gl...
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Article
Open AccessNanopore sequencing reads improve assembly and gene annotation of the Parochlus steinenii genome
Parochlus steinenii is a winged midge from King George Island. It is cold-tolerant and endures the harsh Antarctic winter. Previously, we reported the genome of this midge, but the genome assembly with short read...
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Article
Thin Film Solid Oxide Fuel Cells Operating Below 600°C: A Review
Thin film solid oxide fuel cells (TF-SOFCs) are one of the promising portable power sources in terms of rapid on/off, compact system volume, and high power density. This paper reviews fabrications, and designs...
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Article
Open AccessMolecular and functional signatures in a novel Alzheimer’s disease mouse model assessed by quantitative proteomics
Alzheimer’s disease (AD), the most common neurodegenerative disorder, is characterized by the deposition of extracellular amyloid plaques and intracellular neurofibrillary tangles. To understand the pathologic...
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Chapter and Conference Paper
MapReduce-Based Bulk-Loading Algorithm for Fast Search for Billions of Triples
Due to the development of IT and scientific technology, huge amounts of data are continuously being created and the big data era can be said to have arrived. Therefore, triple store inserting and inquiring int...
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Article
Open AccessFabrication of low-temperature solid oxide fuel cells with a nanothin protective layer by atomic layer deposition
Anode aluminum oxide-supported thin-film fuel cells having a sub-500-nm-thick bilayered electrolyte comprising a gadolinium-doped ceria (GDC) layer and an yttria-stabilized zirconia (YSZ) layer were fabricated...
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Article
Unprecedented high-temperature CO2 selectivity in N2-phobic nanoporous covalent organic polymers
Post-combustion CO2 capture and air separation are integral parts of the energy industry, although the available technologies remain inefficient, resulting in costly energy penalties. Here we report azo-bridged, ...
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Chapter and Conference Paper
Simulation-Based SAM (Surface-to-Air Missile) Analysis in OpenSIM (Open Simulation Engine for Interoperable Models)
Assessing MOE (Measure of Effectiveness) of a weapon system is important as we invest significant efforts to develop the weapon system. OpenSIM (Open Simulation environment for Interoperable Models) has been d...
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Article
In vitro cultures and regeneration of Bienertia sinuspersici (Chenopodiaceae) under increasing concentrations of sodium chloride and carbon dioxide
To study the developmental transition of chloroplasts from C3 to C4 photosynthesis in the terrestrial single-cell C4 species Bienertia sinuspersici, a regeneration protocol was developed. Stem explant material de...
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Article
Structural changes in the vacuole and cytoskeleton are key to development of the two cytoplasmic domains supporting single-cell C4 photosynthesis in Bienertia sinuspersici
Bienertia sinuspersici Akhani has an unusual mechanism of C4 photosynthesis which occurs within individual chlorenchyma cells. To perform C4, the mature cells have two cytoplasmic compartments consisting of a cen...
