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  1. No Access

    Article

    Enhancement of the photodynamic antitumor effect by streptococcal preparation OK-432 in the mouse carcinoma

     Biological response modifier antitumor effects are enhanced by the activation of the host defense mechanisms. We have investigated the antitumor effect of photodynamic therapy (PDT) and/or local administratio...

    Masataka Uehara, Kazuo Sano, Zuo-Lin Wang, Joji Sekine in Cancer Immunology, Immunotherapy (2000)

  2. No Access

    Article

    A case of mucoepidermoid carcinoma with melanin pigmentation manifested in the palate

    This paper describes the first documented case of mucoepidermoid carcinoma (MEC) with melanin pigmentation manifested in the palate. Histopathological sections showed a neoplasm composed of epidermoid, mucous-...

    Joji Sekine, Masanobu Anami, Shuichi Fujita, Michael Vieth in Virchows Archiv (2005)

  3. No Access

    Article

    Oral symptoms including dental erosion in gastroesophageal reflux disease are associated with decreased salivary flow volume and swallowing function

    This preliminary clinical study aimed to evaluate the effects of salivary flow volume and swallowing function on oral symptoms including dental erosion in gastroesophageal reflux disease (GERD).

    Hiroo Yoshikawa, Kenji Furuta, Mayumi Ueno, Masayoshi Egawa in Journal of Gastroenterology (2012)

  4. Article

    Open Access

    Upregulation of aquaporin expression in the salivary glands of heat-acclimated rats

    It is known that aquaporin (AQP) 5 expression in the apical membrane of acinar cells in salivary glands is important for the secretion of saliva in rodents and humans. Although heat acclimation enhances saliva...

    Naotoshi Sugimoto, Kentaro Matsuzaki, Hiroaki Ishibashi, Masao Tanaka in Scientific Reports (2013)

  5. Article

    Open Access

    G196 epitope tag system: a novel monoclonal antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity

    The recognition specificity of monoclonal antibodies (mAbs) has made mAbs among the most frequently used tools in both basic science research and in clinical diagnosis and therapies. Precise determination of t...

    Kasumi Tatsumi, Gyosuke Sakashita, Yuko Nariai, Kosuke Okazaki in Scientific Reports (2017)

  6. Article

    Open Access

    Diagnostic accuracy of oral cancer cytology in a pilot study

    Recently, cytology has been applied to the diagnosis of oral lesions. We aimed to explore the diagnostic accuracy of oral cytology based on the histological diagnosis.

    Joji Sekine, Eiji Nakatani, Katsumi Hideshima, Teruaki Iwahashi in Diagnostic Pathology (2017)

  7. Article

    Open Access

    Oral soft tissue disorders are associated with gastroesophageal reflux disease: retrospective study

    Dental erosion (DE), one of oral hard tissue diseases, is one of the extraoesophageal symptoms defined as the Montreal Definition and Classification of gastroesophageal reflux disease (GERD). However, no study...

    Masaaki Watanabe, Eiji Nakatani, Hiroo Yoshikawa, Takahiro Kanno in BMC Gastroenterology (2017)