1 Result(s)

Article

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human

Several tolerance checkpoints exist throughout B cell development to control autoreactive B cells and prevent the generation of pathogenic autoantibodies. FcγRIIb is an Fc receptor that inhibits B cell activat...

Marion Espéli, Rachael Bashford-Rogers, John M. Sowerby… in Nature Communications (2019)