6 Result(s)
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Article
Open AccessGenomic Mosaicism of the Brain: Origin, Impact, and Utility
Genomic mosaicism describes the phenomenon where some but not all cells within a tissue harbor unique genetic mutations. Traditionally, research focused on the impact of genomic mosaicism on clinical phenotype...
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Article
Publisher Correction: Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management
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Article
Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management
People living with HIV are affected by the chronic consequences of neurocognitive impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve health and extend life. Furthermore,...
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Article
Open AccessLong-term course of anterior spinal cord herniation presenting with an upper motor neuron syndrome: case report illustrating diagnostic and therapeutic implications
Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis ma...
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Article
Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson’s disease
Mobile, sensor-based gait analysis in Parkinson’s disease (PD) facilitates the objective measurement of gait parameters in cross-sectional studies. Besides becoming outcome measures for clinical studies, the a...
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Article
Open AccessOligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?
Oligodendrocytes, the myelinating cells of the central nervous system, mediate rapid action potential conduction and provide trophic support for axonal as well as neuronal maintenance. Their progenitor cell po...
