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Open AccessAssociations between long-term exposure to air pollution and kidney function utilizing electronic healthcare records: a cross-sectional study
Chronic kidney disease (CKD) affects more than 38 million people in the United States, predominantly those over 65 years of age. While CKD etiology is complex, recent research suggests associations with enviro...
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Open AccessCorrection: Modification of the PM2.5- and extreme heat-mortality relationships by historical redlining: A case-crossover study in thirteen U.S. states
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Open AccessLong-term exposure to ambient PM2.5, particulate constituents and hospital admissions from non-respiratory infection
The association between PM2.5 and non-respiratory infections is unclear. Using data from Medicare beneficiaries and high-resolution datasets of PM2.5 and its constituents across 39,296 ZIP codes in the U.S bet...
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Open AccessModification of the PM2.5- and extreme heat-mortality relationships by historical redlining: a case-crossover study in thirteen U.S. states
Redlining has been associated with worse health outcomes and various environmental disparities, separately, but little is known of the interaction between these two factors, if any. We aimed to estimate whethe...
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Open AccessFirst close insight into global daily gapless 1 km PM2.5 pollution, variability, and health impact
Here we retrieve global daily 1 km gapless PM2.5 concentrations via machine learning and big data, revealing its spatiotemporal variability at an exceptionally detailed level everywhere every day from 2017 to 202...
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Annual space weather fluctuations and telomere length dynamics in a longitudinal cohort of older men: the Normative Aging Study
Space weather has been associated with increased risk of cardiovascular diseases in space and flight crew. However, limited research has focused on the ground population, particularly among the elderly who are...
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Everett Mendelsohn, One Colleague’s Remembrances
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Prenatal exposure to ambient particle radioactivity and fetal growth in Eastern Massachusetts
The radioactive component of particulate matter (PM), particle radioactivity (PR), can continue to emit radiation after inhalation. While PR has been associated with other adverse pregnancy outcomes, no studie...
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Open AccessAssociations between long-term exposures to airborne PM2.5 components and mortality in Massachusetts: mixture analysis exploration
Numerous studies have documented PM2.5’s links with adverse health outcomes. Comparatively fewer studies have evaluated specific PM2.5 components. The lack of exposure measurements and high correlation among diff...
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Open AccessLead contamination of public drinking water and academic achievements among children in Massachusetts: a panel study
Public drinking water can be an important source exposure to lead, which can affect children’s cognitive development and academic performance. Few studies have looked at the impact of lead exposures from commu...
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Open AccessMeta-analyses identify DNA methylation associated with kidney function and damage
Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. To extend the knowledg...
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Open AccessEpigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures ...
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Open AccessA national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States
Air pollution may increase risk of Alzheimer’s disease and related dementias (ADRD) in the U.S., but the extent of this relationship is unclear. Here, we constructed two national U.S. population-based cohorts ...
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Open AccessQuantifying the short-term effects of air pollution on health in the presence of exposure measurement error: a simulation study of multi-pollutant model results
Most epidemiological studies estimate associations without considering exposure measurement error. While some studies have estimated the impact of error in single-exposure models we aimed to quantify the effec...
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Open AccessDNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function
The difference between an individual's chronological and DNA methylation predicted age (DNAmAge), termed DNAmAge acceleration (DNAmAA), can capture life-long environmental exposures and age-related physiologic...
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Publisher Correction: Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study
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Open AccessSpatio-temporal associations of air pollutant concentrations, GP respiratory consultations and respiratory inhaler prescriptions: a 5-year study of primary care in the borough of Lambeth, South London
Although the associations of outdoor air pollution exposure with mortality and hospital admissions are well established, few previous studies have reported on primary care clinical and prescribing data. We ass...
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Open AccessEmulating causal dose-response relations between air pollutants and mortality in the Medicare population
Fine particulate matter (PM2.5), ozone (O3), and nitrogen dioxide (NO2) are major air pollutants that pose considerable threats to human health. However, what has been mostly missing in air pollution epidemiology...
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Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study
Air pollution, especially fine particulate matter (PM2.5), may impair cognitive performance1–3, but its short-term impact is poorly understood. We investigated the short-term association of PM2.5 with the cogniti...
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Open AccessAssessing additive effects of air pollutants on mortality rate in Massachusetts
We previously found additive effects of long- and short-term exposures to fine particulate matter (PM2.5), ozone (O3), and nitrogen dioxide (NO2) on all-cause mortality rate using a generalized propensity score (...
