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Article
Open AccessAn inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism
GPR61 is an orphan GPCR related to biogenic amine receptors. Its association with phenotypes relating to appetite makes it of interest as a druggable target to treat disorders of metabolism and body weight, su...
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Article
Assessment of Habitat Suitability for Common Cockles in the Ria the Aveiro Lagoon Under Average and Projected Environmental Conditions
The common cockle Cerastoderma edule is a widespread bivalve species inhabiting estuarine systems across the North East Atlantic, where it provides several ecosystem services, and represents a valuable fishery re...
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Article
Open AccessThe role of transient plasma photonic structures in plasma-based amplifiers
High power lasers have become useful scientific tools, but their large size is determined by their low damage-threshold optical media. A more robust and compact medium for amplifying and manipulating intense l...
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Reference Work Entry In depth
Marine Modelling: Contributions, Advantages, and Areas of Application of Numerical Tools
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Living Reference Work Entry In depth
Marine Modelling: Contributions, Advantages, and Areas of Application of Numerical Tools
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Article
Parasite Assemblages in a Bivalve Host Associated with Changes in Hydrodynamics
Studies on marine community structure and their modulation by horizontal and vertical abiotic gradients have focused on free-living species, neglecting parasites despite their important role in ecosystems. Fie...
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Chapter and Conference Paper
Numerical Characterization of the Douro River Plume
The Douro is one of the largest rivers of the Iberian Peninsula, representing the most important buoyancy source into the Atlantic Ocean on the northwestern Portuguese coast. The main goal of this study is to ...
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Article
Flood risk assessment in a coastal lagoon under present and future scenarios: Ria de Aveiro case study
Floods are one of the major threats to low-lying coastal lagoons, affecting people, socio-economic activities and ecosystem services. This work proposes a methodology to assess present and future flood hazard ...
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Article
Assessment of flood hazard during extreme sea levels in a tidally dominated lagoon
The inundation of coastal regions is recognized as a major threat to people, livelihoods, and the ecosystem health. The assessment of the magnitude of flooding drivers and the flood extension map** are essen...
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Chapter and Conference Paper
Assessment of Image Quality Using a Pseudophakic Eye Model for Refractive Evaluation
In the refractive assessment by optical evaluation based on ray-tracing, the definition of the best focus plane remains a challenge. We simulated 100 pseudophakic eye models using a Montecarlo analysis with ra...
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Article
Establishing the wave climate influence on the morphodynamics of a coastal lagoon inlet
The morphologic changes in estuaries and coastal lagoons are very complex and constitute a challenging task in coastal research. The bathymetric changes result from the combined action of tides, waves, rivers ...
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Article
A shared structural solution for neutralizing ebolaviruses
The surface glycoprotein of the distinct ebolavirus responsible for the largest outbreak yet described (Sudan Gulu) has been crystallized in complex with a novel, neutralizing antibody. The crystal structure a...
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Article
Gamma-rays from harmonically resonant betatron oscillations in a plasma wake
The radiation produced when an intense laser interacts with a solid target could provide a cheaper source of X-rays to synchrotrons and free-electron lasers. But they can also produce short bursts of gamma ray...
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Article
Sensitivity analysis of a morphodynamic modelling system applied to a coastal lagoon inlet
This work investigates the recent morphological changes at the inlet of a complex coastal system (Ria de Aveiro lagoon, Portugal). This study was carried out using bathymetric data analysis and numerical simulati...
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Article
The crystal structures of two spermadhesins reveal the CUB domain fold
Spermadhesins, 12,000–14,000 Mr mammalian proteins, include lectins involved in sperm–egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP...
