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  1. Article

    Open Access

    Profound hypoxemia and hypotension during posterior spinal fusion in a spinal muscular atrophy child with severe scoliosis: a case report

    Anesthesia for spinal muscular atrophy (SMA) patients undergoing spinal deformity surgery is challenging. We report an unusual case of an SMA girl who developed severe intraoperative hypoxemia and hypotension ...

    Qian Shu, Yulei Dong, Weiyun Chen, Jianxiong Shen in BMC Anesthesiology (2024)

  2. Article

    Open Access

    Morphological analysis of isolated hemivertebra: radiographic manifestations related to the severity of congenital scoliosis

    The natural history of congenital scoliosis (CS) caused by hemivertebra varies greatly. This study aimed to explore the association between the morphology of hemivertebra and the severity of CS, since the diag...

    Tianhua Rong, Yang Jiao, Yizhen Huang, Erwei Feng in BMC Musculoskeletal Disorders (2024)

  3. Article

    Open Access

    Unilateral interlaminar fenestration on the convex side provides a reliable access for intrathecal administration of nusinersen in spinal muscular atrophy: a retrospective study

    As the first gene therapy for spinal muscular atrophy (SMA), nusinersen is supposed to be administrated via intrathecal injection regularly for a lifetime. However, for SMA patients with severe spinal deformit...

    Zhen Wang, Erwei Feng, Yang Jiao, Junduo Zhao in Orphanet Journal of Rare Diseases (2023)

  4. No Access

    Article

    Ten-year trends in surgical management of 1207 congenital scoliosis

    To report and analyze development trends in the surgical treatment of congenital scoliosis (CS) in a large CS cohort over a 10-year period.

    Guanfeng Lin, You Du, Shengru Wang, Yang Yang, **aohan Ye in European Spine Journal (2023)

  5. Article

    Correction to: DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer

    Zheng Li, Huizi Lei, Min Luo, Yi Wang, Lei Dong, Yanni Ma, Changzheng Liu in Gastric Cancer (2022)

  6. No Access

    Article

    Surgical treatment of spinal deformities in spinal muscular atrophy: a single-center experience from China

    To report the clinical characteristics and surgical outcomes of scoliosis in patients with spinal muscular atrophy (SMA) from Mainland China.

    Zhen Wang, Erwei Feng, Yang Jiao, Jiachen Lin, Junduo Zhao in European Spine Journal (2022)

  7. Article

    Open Access

    Effects of physiotherapeutic scoliosis-specific exercise in patients with mild juvenile scoliosis

    A combined retrospective and prospective analysis on the therapeutic effect of physiotherapeutic scoliosis-specific exercise (PSSE) in mild juvenile idiopathic scoliosis (JIS) patients.

    Wangshu Yuan, Hai Wang, Keyi Yu, Jianxiong Shen in BMC Musculoskeletal Disorders (2022)

  8. Article

    Open Access

    Apical region correction and global balance: a 3-rods surgical strategy for the treatment of severe and rigid scoliosis

    The treatment of severe and rigid scoliosis is challenging. We developed a surgical strategy for severe and rigid scoliosis since 2014. This study aimed to retrospectively analyze the safety and efficacy of ap...

    Yang Jiao, Haining Tan, Erwei Feng, Zhen Wang, Youxi Lin in BMC Musculoskeletal Disorders (2022)

  9. Article

    Open Access

    Risk factors of postoperative pulmonary complications after primary posterior fusion and hemivertebra resection in congenital scoliosis patients younger than 10 years old: a retrospective study

    Postoperative pulmonary complications are common and associated with morbidity and mortality. Congenital scoliosis is a failure of vertebral formation and/or segmentation arising from abnormal vertebral develo...

    Lulu Ma, Xuerong Yu, Jianguo Zhang, Jianxiong Shen in BMC Musculoskeletal Disorders (2022)

  10. No Access

    Article

    Cross-sectional analysis of associated anomalies and vertebral anomaly location in 1289 surgical congenital scoliosis

    This study systematically analyzed and assessed the interrelationships among vertebral anomaly location, congenital scoliosis (CS) type and associated abnormality prevalence.

    Guanfeng Lin, **ran Chai, Shengru Wang, Yang Yang, Zhe Su, You Du in European Spine Journal (2021)

  11. Article

    Open Access

    Older fusion-surgery age in congenital scoliosis patients is a risk factor for extended length of stay, more estimated blood loss, longer fused segments and higher medical costs: a retrospective study

    Contradictory opinions about whether early correction and fusion surgeries should be performed for congenital scoliosis (CS) patients at a young age exist. The objectives of this study were to analyze the asso...

    **ran Chai, Guanfeng Lin, Shengru Wang, Yang Yang, Zhe Su in BMC Musculoskeletal Disorders (2021)

  12. Article

    Open Access

    Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial

    To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TX...

    Yulei Dong, **qian Liang, Bingdu Tong, Jianxiong Shen in BMC Musculoskeletal Disorders (2021)

  13. No Access

    Article

    Cross-sectional analysis and trend of vertebral and associated anomalies in Chinese congenital scoliosis population: a retrospective study of one thousand, two hundred and eighty nine surgical cases from 2010 to 2019

    The objective of this article is to report associated anomaly incidences of a large CS cohort and analyze interrelationships among vertebral anomaly types and associated abnormalities.

    Guanfeng Lin, **ran Chai, Shengru Wang, Yang Yang in International Orthopaedics (2021)

  14. Article

    Open Access

    Factors and predictive model associated with perioperative complications after long fusion in the treatment of adult non-degenerative scoliosis

    Adult non-degenerative scoliosis accounts for 90% of spinal deformities in young adults. However, perioperative complications and related risk factors of long posterior instrumentation and fusion for the treat...

    Nan Wu, Jiashen Shao, Zhen Zhang, Shengru Wang, Ziquan Li in BMC Musculoskeletal Disorders (2021)

  15. Article

    Open Access

    Growing-rod implantation improves nutrition status of early-onset scoliosis patients: a case series study of minimum 3-year follow-up

    Early onset scoliosis (EOS) may cause malnutrition in affected patients. Growing-rod treatment has been an effective protocol for treating EOS. The objective of this study is to demonstrate whether growing-rod...

    **ngye Li, Zheng Li, Youxi Lin, Haining Tan, Chong Chen, Jianxiong Shen in BMC Surgery (2021)

  16. No Access

    Article

    Posterior fossa decompression with or without duraplasty for patients with chiari type I malformation and basilar impression: a meta-analysis

    To compare clinical effect and safety between posterior fossa decompression with duraplasty (PFDD) and posterior fossa decompression without duraplasty (PFD) in treatment of Chiari type I malformation and basi...

    Siyi Cai, Ye Tian, Jianguo Zhang, Jianxiong Shen, Jianhua Hu in European Spine Journal (2021)

  17. Article

    Open Access

    Comparison between surgical fusion and the growing-rod technique for early-onset neurofibromatosis type-1 dystrophic scoliosis

    Spinal deformities constitute one of the most common types of manifestations of neurofibromatosis type-1 (NF-1), which can lead to either dystrophic or non-dystrophic early-onset scoliosis (EOS). Surgical trea...

    Siyi Cai, Liqiang Cui, Guixing Qiu, Jianxiong Shen in BMC Musculoskeletal Disorders (2020)

  18. Article

    Open Access

    Posterior only instrumented fusion provides incomplete curve control for early-onset scoliosis in type 1 neurofibromatosis

    The mid-long term outcomes of posterior spinal fusion in pediatric neurofibromatosis type 1 (NF-1) patients are rarely reported, so does the effectiveness of itsorthopeidc maintenance function. This study aims...

    Siyi Cai, Zhengyao Li, Guixing Qiu, Jianxiong Shen, Hong Zhao, Yu Zhao in BMC Pediatrics (2020)

  19. No Access

    Article

    The Effect of Traditional Single Growing Rod Technique on Growth of Unsegmented Levels in Mixed Type Congenital Scoliosis

    Tianhua Rong, Jianxiong Shen, Chong Chen, Youxi Lin, Haining Tan in Spine Deformity (2019)

  20. Article

    Open Access

    Predictors for blood loss in pediatric patients younger than 10 years old undergoing primary posterior hemivertebra resection: a retrospective study

    Blood loss during hemivertebra resection may be substantial. Few studies have examined the risk factors of blood loss undergoing hemivertebra resection, especially those in patients under 10 years old.

    Lulu Ma, Jianguo Zhang, Jianxiong Shen, Yu Zhao in BMC Musculoskeletal Disorders (2019)

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