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Article
Dissection of mendelian predisposition and complex genetic architecture of craniovertebral junction malformation
The craniovertebral junction (CVJ) is an anatomically complex region of the axial skeleton that provides protection of the brainstem and the upper cervical spinal cord. Structural malformation of the CVJ gives...
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Article
Open AccessThe identification of PAX7 variants and a potential role of muscle development dysfunction in congenital scoliosis
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Article
Posterior fossa decompression with or without duraplasty for patients with chiari type I malformation and basilar impression: a meta-analysis
To compare clinical effect and safety between posterior fossa decompression with duraplasty (PFDD) and posterior fossa decompression without duraplasty (PFD) in treatment of Chiari type I malformation and basi...
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Article
Open AccessComparison between surgical fusion and the growing-rod technique for early-onset neurofibromatosis type-1 dystrophic scoliosis
Spinal deformities constitute one of the most common types of manifestations of neurofibromatosis type-1 (NF-1), which can lead to either dystrophic or non-dystrophic early-onset scoliosis (EOS). Surgical trea...
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Article
Open AccessCement leakage following percutaneous kyphoplasty in a patient after a posterior lumbar fusion: a case report
Percutaneous kyphoplasty (PKP) has become an important minimally invasive surgical technique for fracture stabilization and pain relief in patients with vertebral compression fractures. However, intraspinal ce...
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Article
Open AccessThe mutational burden and oligogenic inheritance in Klippel-Feil syndrome
Klippel-Feil syndrome (KFS) represents a rare anomaly characterized by congenital fusion of the cervical vertebrae. The underlying molecular etiology remains largely unknown because of the genetic and phenotyp...
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Article
Open AccessPosterior only instrumented fusion provides incomplete curve control for early-onset scoliosis in type 1 neurofibromatosis
The mid-long term outcomes of posterior spinal fusion in pediatric neurofibromatosis type 1 (NF-1) patients are rarely reported, so does the effectiveness of itsorthopeidc maintenance function. This study aims...
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Article
The timing of surgical intervention in the treatment of complete motor paralysis in patients with spinal metastasis
The timing of surgical intervention is important for ambulatory patients with metastatic epidural spinal cord compression (MESCC), while limited studies have focused on non-ambulant patients. The aim of this s...
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Article
Open AccessModeling analysis of secondary inorganic aerosols over China: pollution characteristics, and meteorological and dust impacts
Secondary inorganic aerosols (SIA) are the predominant components of fine particulate matter (PM2.5) and have significant impacts on air quality, human health, and climate change. In this study, the Community Mul...
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Article
Does intraoperative cell salvage system effectively decrease the need for allogeneic transfusions in scoliotic patients undergoing posterior spinal fusion? A prospective randomized study
To determine the safety and efficacy of intraoperative cell salvage system in decreasing the need for allogeneic transfusions in a cohort of scoliosis patients undergoing primary posterior spinal fusion with s...