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Article
Lance-adams syndrome: a report of two cases
Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is se...
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Article
Association of right-to-left shunt with frontal white matter lesions in T2-weighted MR imaging of stroke patients
Cardiac right-to-left shunt (RLS), mainly due to patent foramen ovale (PFO), is a risk factor for paradoxical embolism and stroke. Results of studies about brain lesions in diffusion-weighted imaging (DWI) in ...
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Article
Open AccessTransient filament occlusion of the middle cerebral artery in rats: does the reperfusion method matter 24 hours after perfusion?
There are two widely used transient middle cerebral artery occlusion (MCAO) methods, which differ in the use of unilateral or bilateral carotid artery reperfusion (UNICAR and BICAR). Of the two methods, UNICAR...
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Article
Value of imaging lenticulostriate arteries before middle cerebral artery stenting for the prevention of perforator stroke
In this study, we investigated whether pre-procedural imaging of LSAs would potentially be helpful for preventing LSAs from being covered.
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Article
Relationship between vertebral artery hypoplasia and posterior circulation stroke in Chinese patients
Vertebral artery hypoplasia (VAH), which has been found in about 10 % of normal individuals, does not produce symptoms but may be associated with an increased risk of cerebral posterior circulation ischemic (P...
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Article
Open AccessExogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model
Although a variety of drugs have been used to treat the symptoms of rheumatoid arthritis (RA), none of them are able to cure the disease. Interferon β (IFN-β) has pleiotropic effects on RA, but whether it can ...
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Article
Open AccessDesigner Self-Assemble Peptides Maximize the Therapeutic Benefits of Neural Stem Cell Transplantation for Alzheimer’s Disease via Enhancing Neuron Differentiation and Paracrine Action
The neuropathological hallmarks of Alzheimer’s disease (AD) include the presence of extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques and neuronal loss. Neural stem cell (NSC) is being scruti...
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Article
Pulse pressure as an independent predictor of stroke: a systematic review and a meta-analysis
Recent evidence suggests that pulse pressure (PP) is a strong cardiovascular diseases’ risk factor. We systematically evaluated all relevant studies to determine whether PP can be used as an independent predic...
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Article
Validation of 5-item and 2-item questionnaires in Chinese version of Dizziness Handicap Inventory for screening objective benign paroxysmal positional vertigo
As possible candidate screening instruments for benign paroxysmal positional vertigo (BPPV), studies to validate the Dizziness Handicap Inventory (DHI) sub-scale (5-item and 2-item) and total scores are rare i...
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Article
Open AccessIncreased default mode network connectivity and increased regional homogeneity in migraineurs without aura
The precuneus/posterior cingulate cortex, which has been associated with pain sensitivity, plays a pivotal role in the default mode network. However, information regarding migraine-related alterations in resti...
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Article
Open Accessvon Willebrand factor contributes to poor outcome in a mouse model of intracerebral haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is the most devastating stroke subtype and has no proven treatment. von Willebrand factor (VWF) has recently been demonstrated to promote inflammation processes. The pr...
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Article
Open AccessVisual cortex and cerebellum hyperactivation during negative emotion picture stimuli in migraine patients
Migraines are a common and undertreated disease and often have psychiatric comorbidities; however, the abnormal mechanism of emotional processing in migraine patients has not been well clarified. This study so...
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Article
The sensorimotor network dysfunction in migraineurs without aura: a resting-state fMRI study
Migraine is a common recurrent neurological disorder combining nausea, vomiting, and hypersensitivities to visual, auditory, olfactory and somatosensory stimuli. However, the dysfunction of the sensorimotor ne...
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Article
Open AccessRelationship between intracranial internal carotid artery calcification and enlarged cerebral perivascular space
The association between intracranial internal carotid artery (IICA) calcification and lacunes, white matter hyperintensity (WMH), and cerebral microbleeds (CMBs) has been well researched. However, enlarged cer...
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Article
Open AccessAssessment of gray and white matter structural alterations in migraineurs without aura
Migraine constitute a disorder characterized by recurrent headaches, and have a high prevalence, a high socio-economic burden and severe effects on quality of life. Our previous fMRI study demonstrated that so...
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Article
Open AccessThe Posterior Insula Shows Disrupted Brain Functional Connectivity in Female Migraineurs Without Aura Based on Brainnetome Atlas
Long-term headache attacks may cause human brain network reorganization in patients with migraine. In the current study, we calculated the topologic properties of functional networks based on the Brainnetome a...
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Article
Open AccessRivaroxaban does not influence hemorrhagic transformation in a diabetes ischemic stroke and endovascular thrombectomy model
Managing endovascular thrombectomy (ET) in diabetic ischemic stroke (IS) with novel anticoagulants is challenging due to putative risk of intracerebral hemorrhage. The study evaluates increased hemorrhagic tra...
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Article
Open AccessPrevious chronic symptomatic and asymptomatic cerebral hemorrhage in patients with acute ischemic stroke
Identifying previous chronic cerebral hemorrhage (PCH), especially asymptomatic cases in patients with ischemic stroke, is essential for proper antithrombotic management. The study aimed to further clarify the...
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Article
Open AccessRVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease
Exosomes are lipid-bilayer enclosed nano-sized vesicles that transfer functional cellular proteins, mRNA and miRNAs. Mesenchymal stem cells (MSCs) derived exosomes have been demonstrated to prevent memory defi...
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Article
Cerebellar functional abnormalities in early stage drug-naïve and medicated Parkinson’s disease
Parkinson’s disease (PD) is a progressive neurological degenerative disorder characterized by impaired motor function and non-motor dysfunctions. While recent studies have highlighted the role of the cerebellu...
