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Article
Open AccessMelatonin as an immunomodulator in CD19-targeting CAR-T cell therapy: managing cytokine release syndrome
Chimeric antigen receptor CAR-T cell therapies have ushered in a new era of treatment for specific blood cancers, offering unparalleled efficacy in cases of treatment resistance or relapse. However, the emerge...
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Article
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression
Converting tumor-associated macrophages (TAMs) from the M2 to the M1 phenotype is considered an effective strategy for cancer therapy. TRAF3 is known to regulate NF-κB signaling. However, the role of TRAF3 in ...
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Article
Estimating security of the quantum key distribution from the guesswork
Quantum key distribution can provide information-theoretic security keys. In practice, the eavesdropper may attack the transmitted quantum state, which makes some information leakage to the generated key. The ...
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Article
Open AccessTRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis
TRK-fused gene (TFG) is known to be involved in protein secretion and plays essential roles in an antiviral innate immune response. However, its function in LPS-induced inflammation and pyroptotic cell death i...
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Article
Composite Quantile Estimation in Partial Functional Linear Regression Model Based on Polynomial Spline
In this paper, we consider composite quantile regression for partial functional linear regression model with polynomial spline approximation. Under some mild conditions, the convergence rates of the estimators...
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Article
Open AccessTranscriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma
CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study,...
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Article
TBK1 as a regulator of autoimmunity and antitumor immunity
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Article
An arbitrated quantum signature protocol based on the chained CNOT operations encryption
At present, the encryption scheme used by most arbitrated quantum signature (AQS) protocols is quantum one-time pad (QOTP) which encrypts data qubit by qubit. Though QOTP can achieve high security for data enc...
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Article
A multiparty error-correcting method for quantum secret sharing
Quantum secret sharing (QSS) refers to the process in which the secret is divided into several sub-secrets and sent to different users utilizing quantum technology. Only the user belonging to a specific subset...
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Article
One-insider attack of quantum secret sharing protocol with collective eavesdrop**-check
Recently, a kind of quantum secret sharing protocol with collective eavesdrop** check was proposed by Lin et al. In this paper, we present a one-insider attack against Lin’s three-party protocol. With the me...
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Article
Consistent nonnegative estimates of variance components
In this paper, the estimation of variance components in the linear mixed model with two random effects is investigated. The class of combination estimates based on the quadratic invariant statistics and consis...