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  1. Article

    Open Access

    Establishment of a piglet model for peritoneal metastasis of ovarian cancer

    A piglet model for peritoneal metastasis (PM) of ovarian cancer was developed. It will contribute to establishing innovative chemotherapeutical and surgical strategies without any limitation on rodent models.

    Eun Ji Lee, Soo ** Park, Aeran Seol, Hyunji Lim in Journal of Translational Medicine (2022)

  2. Article

    Open Access

    β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis

    Adenomyosis is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium. Adenomyosis is a common cause of dysmenorrhea, menorrhagia, and chronic pelvic pain but is often ...

    Jung-Yoon Yoo, Bon Jeong Ku, Tae Hoon Kim, Jong Il Ahn in Experimental & Molecular Medicine (2020)

  3. No Access

    Article

    Integrins expressed on the surface of human endometrial stromal cells derived from a female patient experiencing spontaneous abortion

    Here, as a basic study in revealing the correlation between extracellular matrix components and spontaneous abortion, we defined the types of integrins expressed on the surface of endometrial stromal (ES) cell...

    Jie Ohn Sohn, Hye ** Park, Se Hee Kim, Min Ji Kim, Hyun ** Song in Human Cell (2020)

  4. Article

    Open Access

    G-protein coupled receptor 64 (GPR64) acts as a tumor suppressor in endometrial cancer

    Endometrial cancer is the most common gynecological cancer. G-protein coupled receptor 64 (GPR64) belongs to a family of adhesion GPCRs and plays an important role in male fertility. However, the function of G...

    Jong Il Ahn, Jung-Yoon Yoo, Tae Hoon Kim, Young Im Kim, Russell R. Broaddus in BMC Cancer (2019)

  5. No Access

    Article

    Silver-Nanowires Coated Pitch-Tuned Coiled Polymer Actuator for Large Contractile Strain under Light-Loading

    We report a pitch-tuned coiled polymer actuator (CPA) with a compliant silver-nanowires (AgNWs) electrode. For a pitch-tuning of the CPA, we sequentially implement a twist-insertion for coiling a nylon-6 fiber...

    Dongbum Pyo, Jeong-Mook Lim, Seongcheol Mun in International Journal of Precision Enginee… (2018)

  6. Article

    Open Access

    Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

    Embryonic stem cells (ESCs) maintain pluripotency through unique epigenetic states. When ESCs commit to a specific lineage, epigenetic changes in histones and DNA accompany the transition to specialized cell t...

    Kun-Yong Kim, Yoshiaki Tanaka, Juan Su, Bilal Cakir, Yangfei **ang in Nature Communications (2018)

  7. Article

    Open Access

    Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development via a unique transcriptional network

    Acquisition of pluripotency by transcriptional regulatory factors is an initial developmental event that is required for regulation of cell fate and lineage specification during early embryonic development. Th...

    Jae Yong Han, Hyo Gun Lee, Young Hyun Park in Journal of Animal Science and Biotechnology (2018)

  8. Article

    Open Access

    G-protein coupled receptor 64 is required for decidualization of endometrial stromal cells

    Although GPR64 has an important role for male fertility, its physiological roles in the female reproductive system are still unknown. In the present study, immunohistochemical analysis reveals a spatiotemporal...

    Jung-Yoon Yoo, Jong Il Ahn, Tae Hoon Kim, Sungryul Yu, Ji Yeon Ahn in Scientific Reports (2017)

  9. No Access

    Article

    Medium composition for effective slow freezing of embryonic cell lines derived from marine medaka (Oryzias dancena)

    This study was conducted to identify optimal medium composition for freezing Oryzias dancena embryonic cell lines. Different freezing media consisting of various concentration of dimethyl sulfoxide (DMSO), fetal ...

    Min Sung Kim, Seung Tae Lee, Jeong Mook Lim, Seung Pyo Gong in Cytotechnology (2016)

  10. No Access

    Chapter and Conference Paper

    Estimating the Number of Clusters with Database for Texture Segmentation Using Gabor Filter

    This paper addresses a novel solution of the problem of image segmentation by its texture using Gabor filter. Texture segmentation has been worked well by using Gabor filter, but there still is a problem; the ...

    Minkyu Kim, Jeong-Mook Lim, Heesook Shin, Changmok Oh in Computer Vision Systems (2015)

  11. No Access

    Protocol

    Laboratory Control and Basic Culture Protocols for Stem Cell Self-Renewal

    In this report, we introduce a standard protocol for stem cell self-renewal in vitro. Both fundamental and major procedures of stem cell manipulation, which are required for somatic cell coculture and self-ren...

    Jeong Mook Lim, Yoon Mi Jo, Ji Yeon Ahn in Stem Cell Renewal and Cell-Cell Communication (2015)

  12. No Access

    Article

    Establishment condition and characterization of heart-derived cell culture in Siberian sturgeon (Acipenser baerii)

    This study was conducted to establish the efficient condition for stable derivation of heart-derived cell culture in Siberian sturgeon (Acipenser baerii). Three factors including isolation methods, cell densities...

    Min Sung Kim, Yoon Kwon Nam, Chulhong Park in In Vitro Cellular & Developmental Biology … (2014)

  13. No Access

    Article

    The establishment of mouse embryonic stem cell cultures on 96-well plates for high-throughput screening

    Embryonic stem (ES) cells can be valuable for monitoring differentiation processes and for improving applications in basic developmental biology. The application of ES cells can be a useful tool for drug disco...

    Meeyoung Cho, Tae-Jun Cho, Jeong Mook Lim, Gene Lee, Jae** Cho in Molecules and Cells (2013)

  14. No Access

    Chapter and Conference Paper

    SHIFT: Interactive Smartphone Bumper Case

    This paper introduces a novel smartphone bumper case providing an interactive touch sense and a realistic physical feeling. The thin and rapidly responding film-like actuator installed in the case simulates a ...

    Jong-uk Lee, Jeong-Mook Lim, Heesook Shin in Haptics: Perception, Devices, Mobility, an… (2012)

  15. Article

    Open Access

    Genetic and cellular aspects of the establishment of histocompatible stem cells: information gained from an animal model

    The establishment of patient-specific histocompatible stem cells may be an alternative for overcoming current limitations in stem cell engineering. We are develo** an animal model to assist the establishment...

    Jeong Mook Lim, Seung Pyo Gong in BMC Proceedings (2011)

  16. Article

    Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

    Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through acti...

    Mi-Kyung Kim, Kidong Kim, Jae Yong Han, Jeong Mook Lim, Yong Sang Song in Genes & Nutrition (2011)

  17. Article

    Open Access

    A set of stage-specific gene transcripts identified in EK stage X and HH stage 3 chick embryos

    The embryonic developmental process in avian species is quite different from that in mammals. The first cleavage begins 4 h after fertilization, but the first differentiation does not occur until laying of the...

    Bo Ram Lee, Heebal Kim, Tae Sub Park, Sun** Moon, Seoae Cho in BMC Developmental Biology (2007)

  18. Article

    Open Access

    Gene expression profiling of chicken primordial germ cell ESTs

    Germ cells are the only cell type that can penetrate from one generation to next generation. At the early embryonic developmental stages, germ cells originally stem from primordial germ cells, and finally diff...

    Jae Yong Han, Tae Sub Park, ** Nam Kim, Mi A Kim, Dajeong Lim in BMC Genomics (2006)