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Article
Open AccessEstablishment of a piglet model for peritoneal metastasis of ovarian cancer
A piglet model for peritoneal metastasis (PM) of ovarian cancer was developed. It will contribute to establishing innovative chemotherapeutical and surgical strategies without any limitation on rodent models.
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Article
Open Accessβ-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
Adenomyosis is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium. Adenomyosis is a common cause of dysmenorrhea, menorrhagia, and chronic pelvic pain but is often ...
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Article
Integrins expressed on the surface of human endometrial stromal cells derived from a female patient experiencing spontaneous abortion
Here, as a basic study in revealing the correlation between extracellular matrix components and spontaneous abortion, we defined the types of integrins expressed on the surface of endometrial stromal (ES) cell...
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Article
Open AccessG-protein coupled receptor 64 (GPR64) acts as a tumor suppressor in endometrial cancer
Endometrial cancer is the most common gynecological cancer. G-protein coupled receptor 64 (GPR64) belongs to a family of adhesion GPCRs and plays an important role in male fertility. However, the function of G...
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Article
Silver-Nanowires Coated Pitch-Tuned Coiled Polymer Actuator for Large Contractile Strain under Light-Loading
We report a pitch-tuned coiled polymer actuator (CPA) with a compliant silver-nanowires (AgNWs) electrode. For a pitch-tuning of the CPA, we sequentially implement a twist-insertion for coiling a nylon-6 fiber...
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Article
Open AccessUhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Embryonic stem cells (ESCs) maintain pluripotency through unique epigenetic states. When ESCs commit to a specific lineage, epigenetic changes in histones and DNA accompany the transition to specialized cell t...
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Article
Open AccessAcquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development via a unique transcriptional network
Acquisition of pluripotency by transcriptional regulatory factors is an initial developmental event that is required for regulation of cell fate and lineage specification during early embryonic development. Th...
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Article
Open AccessG-protein coupled receptor 64 is required for decidualization of endometrial stromal cells
Although GPR64 has an important role for male fertility, its physiological roles in the female reproductive system are still unknown. In the present study, immunohistochemical analysis reveals a spatiotemporal...
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Article
Medium composition for effective slow freezing of embryonic cell lines derived from marine medaka (Oryzias dancena)
This study was conducted to identify optimal medium composition for freezing Oryzias dancena embryonic cell lines. Different freezing media consisting of various concentration of dimethyl sulfoxide (DMSO), fetal ...
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Chapter and Conference Paper
Estimating the Number of Clusters with Database for Texture Segmentation Using Gabor Filter
This paper addresses a novel solution of the problem of image segmentation by its texture using Gabor filter. Texture segmentation has been worked well by using Gabor filter, but there still is a problem; the ...
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Protocol
Laboratory Control and Basic Culture Protocols for Stem Cell Self-Renewal
In this report, we introduce a standard protocol for stem cell self-renewal in vitro. Both fundamental and major procedures of stem cell manipulation, which are required for somatic cell coculture and self-ren...
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Article
Establishment condition and characterization of heart-derived cell culture in Siberian sturgeon (Acipenser baerii)
This study was conducted to establish the efficient condition for stable derivation of heart-derived cell culture in Siberian sturgeon (Acipenser baerii). Three factors including isolation methods, cell densities...
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Article
The establishment of mouse embryonic stem cell cultures on 96-well plates for high-throughput screening
Embryonic stem (ES) cells can be valuable for monitoring differentiation processes and for improving applications in basic developmental biology. The application of ES cells can be a useful tool for drug disco...
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Chapter and Conference Paper
SHIFT: Interactive Smartphone Bumper Case
This paper introduces a novel smartphone bumper case providing an interactive touch sense and a realistic physical feeling. The thin and rapidly responding film-like actuator installed in the case simulates a ...
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Article
Open AccessGenetic and cellular aspects of the establishment of histocompatible stem cells: information gained from an animal model
The establishment of patient-specific histocompatible stem cells may be an alternative for overcoming current limitations in stem cell engineering. We are develo** an animal model to assist the establishment...
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Article
Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer
Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through acti...
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Article
Open AccessA set of stage-specific gene transcripts identified in EK stage X and HH stage 3 chick embryos
The embryonic developmental process in avian species is quite different from that in mammals. The first cleavage begins 4 h after fertilization, but the first differentiation does not occur until laying of the...
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Article
Open AccessGene expression profiling of chicken primordial germ cell ESTs
Germ cells are the only cell type that can penetrate from one generation to next generation. At the early embryonic developmental stages, germ cells originally stem from primordial germ cells, and finally diff...