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Article
Open AccessPET/CT imaging 2 h after injection of [18F]PSMA-1007 can lead to higher staging of prostate cancer than imaging after 1 h
[18F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. Current guidelines recommend imaging 90–120 min after injection but strong d...
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Article
Open AccessHead-to-head comparison of a Si-photomultiplier-based and a conventional photomultiplier-based PET-CT system
A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing...
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Article
Open AccessOptimization of [18F]PSMA-1007 PET-CT using regularized reconstruction in patients with prostate cancer
Prostate-specific membrane antigen (PSMA) radiotracers such as [18F]PSMA-1007 used with positron emission tomography-computed tomography (PET-CT) is promising for initial staging and detection of recurrent diseas...
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Article
Open AccessComparison of conventional and Si-photomultiplier-based PET systems for image quality and diagnostic performance
A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and...
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Article
Open AccessComparison between silicon photomultiplier-based and conventional PET/CT in patients with suspected lung cancer—a pilot study
Lung cancer is one of the most common cancers in the world. Early detection and correct staging are fundamental for treatment and prognosis. Positron emission tomography with computed tomography (PET/CT) is re...
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Article
Open AccessImpact of acquisition time and penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm on a Si-photomultiplier-based PET-CT system for 18F-FDG
Block-sequential regularized expectation maximization (BSREM), commercially Q. Clear (GE Healthcare, Milwaukee, WI, USA), is a reconstruction algorithm that allows for a fully convergent iterative reconstructi...
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Article
Open AccessImpact of penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm for 18F-fluorocholine PET-CT regarding image quality and interpretation
Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-...
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Article
Open AccessFully quantitative cardiovascular magnetic resonance myocardial perfusion ready for clinical use: a comparison between cardiovascular magnetic resonance imaging and positron emission tomography
Recent studies have shown that quantification of myocardial perfusion (MP) at stress and myocardial perfusion reserve (MPR) offer additional diagnostic and prognostic information compared to qualitative and se...
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Chapter
Quality Control of Gamma Cameras, SPECT/CT and PET/CT Units
The image of the activity distribution reproduced by a gamma camera or a PET camera is influenced by the properties and the condition of the camera. Regular quality control of the camera is of decisive importa...
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Article
Inhomogeneous activity distribution of 177Lu-DOTA0-Tyr3-octreotate and effects on somatostatin receptor expression in human carcinoid GOT1 tumors in nude mice
The aim of this study was to investigate the activity distribution in neouroendocrine tumors after diagnostic, or therapeutic, amounts of [177Lu-DOTA0-Tyr3]-octreotate and to investigate how the activity distribu...
