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  1. Article

    Open Access

    Comparison of conventional and Si-photomultiplier-based PET systems for image quality and diagnostic performance

    A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and...

    Jenny Oddstig, Sigrid Leide Svegborn, Helen Almquist, Ulrika Bitzén in BMC Medical Imaging (2019)

  2. Article

    Open Access

    Impact of acquisition time and penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm on a Si-photomultiplier-based PET-CT system for 18F-FDG

    Block-sequential regularized expectation maximization (BSREM), commercially Q. Clear (GE Healthcare, Milwaukee, WI, USA), is a reconstruction algorithm that allows for a fully convergent iterative reconstructi...

    Elin Trägårdh, David Minarik, Helén Almquist, Ulrika Bitzén in EJNMMI Research (2019)

  3. Article

    Open Access

    Impact of penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm for 18F-fluorocholine PET-CT regarding image quality and interpretation

    Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-...

    Mimmi Bjöersdorff, Jenny Oddstig, Nina Karindotter-Borgendahl in EJNMMI Physics (2019)

  4. Article

    Open Access

    Pre-treatment 18F-choline PET/CT is prognostic for biochemical recurrence, development of bone metastasis, and cancer specific mortality following radical local therapy of high-risk prostate cancer

    The aim of this study was to determine whether lymph node metastasis on pre-treatment 18F-choline PET/CT is an independent prognostic factor for biochemical recurrence (BCR), skeletal metastasis, and cancer speci...

    Henrik Kjölhede, Helén Almquist, Kerstin Lyttkens in European Journal of Hybrid Imaging (2018)

  5. Article

    Open Access

    A population-based study of the clinical utility of 18F–choline PET/CT for primary metastasis staging of high-risk prostate cancer

    The clinical utility of 18F–choline positron emission tomography fused with computed tomography (PET/CT) in all men with high-risk prostate cancer is still uncertain, because of selection of patients in previous ...

    Henrik Kjölhede, Helen Almquist, Kerstin Lyttkens in European Journal of Hybrid Imaging (2017)

  6. No Access

    Article

    18F-choline PET/CT for early detection of metastases in biochemical recurrence following radical prostatectomy

    Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1–2 ng/mL. The value of positron emis...

    Henrik Kjölhede, Göran Ahlgren, Helen Almquist in World Journal of Urology (2015)

  7. No Access

    Article

    Concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma

    To determine if PET reporting criteria for the Response Adapted Treatment in Hodgkin Lymphoma (RATHL) trial could enable satisfactory agreement to be reached between ‘core’ laboratories operating in different ...

    Sally F. Barrington, Wendi Qian in European Journal of Nuclear Medicine and M… (2010)

  8. No Access

    Article

    Clinical implication of down-scatter in attenuation-corrected myocardial SPECT

    Interpretation of myocardial perfusion single photon emission computed tomography (SPECT) studies is hampered by attenuation artifacts. Attenuation correction methods with simultaneous emission and transmissio...

    Helén Almquist, Håkan Arheden, Ann-Helen Arvidsson in Journal of Nuclear Cardiology (1999)

  9. No Access

    Article

    Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method

    A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coeff...

    Helén Almquist, John Palmer, Michael Ljungberg in European Journal of Nuclear Medicine (1990)