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Article
Open AccessComparison of conventional and Si-photomultiplier-based PET systems for image quality and diagnostic performance
A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and...
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Article
Open AccessImpact of acquisition time and penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm on a Si-photomultiplier-based PET-CT system for 18F-FDG
Block-sequential regularized expectation maximization (BSREM), commercially Q. Clear (GE Healthcare, Milwaukee, WI, USA), is a reconstruction algorithm that allows for a fully convergent iterative reconstructi...
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Article
Open AccessImpact of penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm for 18F-fluorocholine PET-CT regarding image quality and interpretation
Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-...
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Article
Open AccessPre-treatment 18F-choline PET/CT is prognostic for biochemical recurrence, development of bone metastasis, and cancer specific mortality following radical local therapy of high-risk prostate cancer
The aim of this study was to determine whether lymph node metastasis on pre-treatment 18F-choline PET/CT is an independent prognostic factor for biochemical recurrence (BCR), skeletal metastasis, and cancer speci...
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Article
Open AccessA population-based study of the clinical utility of 18F–choline PET/CT for primary metastasis staging of high-risk prostate cancer
The clinical utility of 18F–choline positron emission tomography fused with computed tomography (PET/CT) in all men with high-risk prostate cancer is still uncertain, because of selection of patients in previous ...
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Article
18F-choline PET/CT for early detection of metastases in biochemical recurrence following radical prostatectomy
Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1–2 ng/mL. The value of positron emis...
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Article
Concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma
To determine if PET reporting criteria for the Response Adapted Treatment in Hodgkin Lymphoma (RATHL) trial could enable satisfactory agreement to be reached between ‘core’ laboratories operating in different ...
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Article
Clinical implication of down-scatter in attenuation-corrected myocardial SPECT
Interpretation of myocardial perfusion single photon emission computed tomography (SPECT) studies is hampered by attenuation artifacts. Attenuation correction methods with simultaneous emission and transmissio...
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Article
Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method
A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coeff...