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Article
Open AccessAssessing the importance of primary care diagnoses in the UK Biobank
The UK Biobank has made general practitioner (GP) data (censoring date 2016–2017) available for approximately 45% of the cohort, whilst hospital inpatient and death registry (referred to as “HES/Death”) data a...
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Article
Open AccessKidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank
Associations between kidney function and dementia risk are inconclusive. Chronic kidney disease (CKD) severity is determined by levels of both estimated glomerular filtration rate (eGFR) and the urine albumin ...
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Article
Open AccessAssessing agreement between different polygenic risk scores in the UK Biobank
Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratification. However, there are limited investigations on how different PRS diverge from each other in risk predic...