Skip to main content

7 Result(s)

within Jeehye Park Remove this filter

and

  1. No Access

    Article

    LONRF2 is a gatekeeper against protein aggregation in aging neurons

    Neuronal aging is highly associated with misfolded protein aggregates that predispose to neurodegeneration, but the cellular factors that are involved in removing misfolded proteins are yet to be identified. I...

    Mohieldin M. M. Youssef, Jeehye Park in Nature Aging (2023)

  2. No Access

    Article

    Differences in Proportion of N-acetyllactosamine and O-acetylated Sialic Acid Have No Significant Effect on the Pharmacokinetics and Biological Activity of Darbepoetin Alfa

    Darbepoetin alfa is used to treat anemia in patients with chronic renal failure and is a therapeutic glycoprotein with five N-glycosylation sites and one O-glycosylation site. Since the glycosylation of therap...

    Won Jeong Lee, Hookeun Oh, Inseong Choi… in Biotechnology and Bioprocess Engineering (2022)

  3. Article

    Open Access

    Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS

    A missense mutation, S85C, in the MATR3 gene is a genetic cause for amyotrophic lateral sclerosis (ALS). It is unclear how the S85C mutation affects MATR3 function and contributes to disease. Here, we develop a m...

    Ching Serena Kao, Rebekah van Bruggen, Jihye Rachel Kim… in Nature Communications (2020)

    Download PDF (4348 KB) View Article

  4. No Access

    Article

    Zoledronic acid and skeletal-related events in patients with bone metastatic cancer or multiple myeloma

    Investigations of ZA effectiveness using large, real-world databases are rare. We examined whether zoledronic acid (ZA) decreased the risk of skeletal-related events (SREs) among patients with bone metastases ...

    Ha-Lim Jeon, In-Sun Oh, Yeon-Hee Baek… in Journal of Bone and Mineral Metabolism (2020)

  5. No Access

    Chapter and Conference Paper

    Impact of Climate Change on Paddy Production in Malaysia: Empirical Analysis at the National and State Level Experience

     is the staple diet of the people in Malaysia. Nearly 70% of the rice is produced locally and the rest is imported. Paddy production is highly susceptible to extreme weather events such as droughts and flo...

    Gamini Herath, Akram Hasanov, Jeehye Park in Proceedings of the Thirteenth Internationa… (2020)

  6. No Access

    Article

    RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

    Many neurodegenerative disorders, such as Alzheimer’s, Parkinson’s and polyglutamine diseases, share a common pathogenic mechanism: the abnormal accumulation of disease-causing proteins, due to either the muta...

    Jeehye Park, Ismael Al-Ramahi, Qiumin Tan, Nissa Mollema, Javier R. Diaz-Garcia… in Nature (2013)

  7. No Access

    Article

    Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

    The PINK1 gene was recently implicated in autosomal recessive juvenile Parkinson's disease. Two groups have studied the equivalent gene in the fruitfly Drosophila, and find that it localizes to mitochondria in vi...

    Jeehye Park, Sung Bae Lee, Sungkyu Lee, Yongsung Kim, Saera Song, Sunhong Kim… in Nature (2006)