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Article
Open AccessImpact of the metabolic syndrome on prevalence and survival in motor neuron disease: a retrospective case series
Metabolic dysfunction is an important factor in the pathogenesis of motor neuron disease, but its prevalence and association with survival in this disorder is unknown. We hypothesized that patients with motor ...
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Article
Open AccessRandomized crossover trial of a modified ketogenic diet in Alzheimer’s disease
Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet imp...
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Article
Open AccessInhibition of mouse brown adipocyte differentiation by second-generation antipsychotics
Brown adipose tissue is specialized to burn lipids for thermogenesis and energy expenditure. Second-generation antipsychotics (SGA) are the most commonly used drugs for schizophrenia with several advantages ov...
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Article
A dual role for MYB60 in stomatal regulation and root growth of Arabidopsis thaliana under drought stress
In response to environmental challenges, plant cells activate several signaling pathways that trigger the expression of transcription factors. Arabidopsis MYB60 was reported to be involved in stomatal regulation ...
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Article
Enhanced level of anthocyanin leads to increased salt tolerance in arabidopsis PAP1-D plants upon sucrose treatment
Many lines of evidence indicate that the increased activity of enzymes involved in phenolic compound biosynthesis and the subsequent accumulation of these compounds correlate with plant resistance to abiotic a...
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Article
The ethylene signaling pathway has a negative impact on sucrose-induced anthocyanin accumulation in Arabidopsis
In an attempt to understand the complex regulatory mechanisms underlying sucrose-induced flavonoid biosynthesis, we examined several Arabidopsis mutants with altered anthocyanin accumulation. We determined tha...
