5 Result(s)
within
Jay R. Perrier
English
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Article
Open AccessLongitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques
Non-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation, development of radiation biodosimetry, and for understanding the impact of ...
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Article
Open AccessMachine learning methodology for high throughput personalized neutron dose reconstruction in mixed neutron + photon exposures
We implemented machine learning in the radiation biodosimetry field to quantitatively reconstruct neutron doses in mixed neutron + photon exposures, which are expected in improvised nuclear device detonations....
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Article
Open AccessDevelopment of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage
Following a large-scale radiological incident, there is a need for FDA-approved biodosimetry devices and biomarkers with the ability to rapidly determine past radiation exposure with sufficient accuracy for ea...
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Article
Open AccessA High Throughput Approach to Reconstruct Partial-Body and Neutron Radiation Exposures on an Individual Basis
Biodosimetry-based individualized reconstruction of complex irradiation scenarios (partial-body shielding and/or neutron + photon mixtures) can improve treatment decisions after mass-casualty radiation-related...
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Article
Open AccessCandidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model
After a radiological incident, there is an urgent need for fast and reliable bioassays to identify radiation-exposed individuals within the first week post exposure. This study aimed to identify candidate radi...
