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Javier Larrasa-Alonso
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Article
Functional Impact and Regulation of Alternative Splicing in Mouse Heart Development and Disease
Alternative splicing (AS) plays a major role in the generation of transcript diversity. In the heart, roles have been described for some AS variants, but the global impact and regulation of AS patterns are poo...
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Article
Open AccessSIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesis
Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results show that SIX1 also acts as a repressor of cell senescence, an antiproliferative response with a key r...
