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Article
Open AccessQuestion banks: credit? Or debit? A qualitative exploration of their use among medical students
Online question banks are the most widely used education resource amongst medical students. Despite this there is an absence of literature outlining how and why they are used by students. Drawing on Deci and R...
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Article
One More Time, Does Money Buy Happiness?
This paper integrates multiple positions on the relationship between money and well-being, commonly referred to as happiness. An aggregation of prior work appears to suggest that money does buy happiness, but ...
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Article
Accuracy in Predicting Repetitions to Task Failure in Resistance Exercise: A Sco** Review and Exploratory Meta-analysis
Prescribing repetitions relative to task failure is an emerging approach to resistance training. Under this approach, participants terminate the set based on their prediction of the remaining repetitions left ...
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Article
Open AccessUsing medical reality television as a technology-enhanced learning strategy to provide authentic patient care experiences during clinical placements: a case study research investigation
Over the last decade, the use of technology-enhanced learning (TEL) has rapidly expanded and diversified. Since the COVID-19 pandemic, there is a growing demand for distance and online learning strategies to s...
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Article
A phase I dose finding study of intravenous voriconazole in pediatric patients undergoing hematopoietic cell transplantation
To optimize voriconazole dosing in pediatric hematopoietic cell transplantation (HCT), we conducted a phase I study with a modified 3 + 3 dose-escalation followed by an expansion cohort at the maximum tolerate...
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Article
Determination of Rate and Extent of Scopolamine Release from Transderm Scōp® Transdermal Drug Delivery Systems in Healthy Human Adults
To estimate strength of a scopolamine transdermal delivery system (TDS) in vivo, using residual drug vs. pharmacokinetic analyses with the goal of scientifically supporting a single and robust method for use acro...
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Article
Develo** delirium best practice: a systematic review of education interventions for healthcare professionals working in inpatient settings
To systematically review the literature pertaining to the quality, impact and sustainability of education interventions that focus on improving delirium care by healthcare professionals working in inpatient se...
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Article
Open AccessGenetically engineered minipigs model the major clinical features of human neurofibromatosis type 1
Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin 1 (NF1). NF1 patients present with a variety of clinical manifestations and are predisposed to cancer development. Many NF1...
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Article
Sensitive Determination of Fentanyl in Low-Volume Serum Samples by LC-MS/MS
Fentanyl is a widely used drug in the management of pain. Present LC-MS/MS methods for analysis of fentanyl require a large volume of serum, but yet the sensitivity was at about 50 pg/mL. Here, we report a mod...
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Article
High intensity interval training does not impair strength gains in response to resistance training in premenopausal women
To compare the increases in upper- and lower-body muscle strength in premenopausal women performing resistance training (RT) alone or alongside concurrent high-intensity interval training (CT).
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Article
A Review of the Acute Effects and Long-Term Adaptations of Single- and Multi-Joint Exercises during Resistance Training
Resistance exercises can be considered to be multi-joint (MJ) or single-joint (SJ) in nature. Many strength coaches, trainers, and trainees believe that adding SJ exercises to a resistance training (RT) progra...
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Article
Open AccessA higher effort-based paradigm in physical activity and exercise for public health: making the case for a greater emphasis on resistance training
It is well known that physical activity and exercise is associated with a lower risk of a range of morbidities and all-cause mortality. Further, it appears that risk reductions are greater when physical activi...
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Article
Authors’ Reply to Ribeiro et al.: “A Review of the Acute Effects and Long-Term Adaptations of Single- and Multi-Joint Exercises During Resistance Training”
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Article
High- and Low-Load Resistance Training: Interpretation and Practical Application of Current Research Findings
Our current state of knowledge regarding the load (lighter or heavier) lifted in resistance training programmes that will result in ‘optimal’ strength and hypertrophic adaptations is unclear. Despite this, pos...
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Article
Scientific Rigour: a Heavy or Light Load to Carry?
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Article
Sunitinib LC–MS/MS Assay in Mouse Plasma and Brain Tissue: Application in CNS Distribution Studies
Sunitinib malate is a multi-targeted tyrosine-kinase inhibitor, currently in clinical trials for glioma. Previously developed methods for preclinical studies in species such as mice have either employed high-p...
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Chapter
Liver Regeneration and Tissue Engineering
The liver is one of the largest and most complex organs in the human body. It is a vital organ weighing about 1,500 g and it continuously performs over 500 different functions. As a result, the liver is a vita...
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Chapter and Conference Paper
Performance Monitoring, Supervisory Support, and Job Characteristics and Their Impact on Employee Well-Being Amongst Four Samples of Call Centre Agents in South Africa
This paper reports a descriptive comparison of selected aspects of work experience reflected by four groups of employees drawn from four contrasting call center environments based in the Gauteng Province of So...
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Chapter and Conference Paper
Problematic Internet Use in South African Information Technology Workers
The majority of studies that have looked at Internet addiction and problematic Internet use have focused either on university students or high school pupils as groups at high risk of experiencing problems as a...
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Article
The Incidence, Management, and Complications of Dysphagia in Patients with Medullary Strokes Admitted to a Rehabilitation Unit
The objective of this study was to examine the frequency of dysphagia symptoms and related consequences in medullary stroke patients admitted to a stroke rehabilitation unit. A chart review of a cohort of 563 ...