8 Result(s)
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Article
Computational prediction of transcription factor binding sites based on an integrative approach incorporating genomic and epigenomic features
Transcription factor binding sites (TFBSs) are often predicted by sequence-based methods that use a position weight matrix or consensus sequences. However, the degeneracy of TFBSs makes the prediction of them ...
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Article
A clustering method for next-generation sequences of bacterial genomes through multiomics data map**
With various ‘omics’ data becoming available recently, new challenges and opportunities are provided for researches on the assembly of next-generation sequences. As an attempt to utilize novel opportunities, w...
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Article
Effects of omics data combinations on in silico tumor-normal tissue classification
A disease can be characterized by various attributes such as genomic, epigenetic, and transcriptomic features beyond physiological symptoms. The accumulation of vast datasets allows us to investigate the relat...
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Article
Open AccessReconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes
Reconstruction of ancestral karyotypes is critical for our understanding of genome evolution, allowing for the identification of the gross changes that shaped extant genomes. The identification of such changes...
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Article
Markov chain Monte Carlo simulation of a Bayesian mixture model for gene network inference
Simultaneous measurement of gene expression level for thousands of genes contains the rich information about many different aspects of biological mechanisms. A major computational challenge is to find methods ...
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Article
Open AccessPopulation analysis of the Korean native duck using whole-genome sequencing data
Advances in next-generation sequencing technologies have provided an opportunity to perform population-level comparative genomic analysis to discover unique genomic characteristics of domesticated animals. Duc...
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Article
Open AccessComparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig
DNA methylation and demethylation at CpG islands is one of the main regulatory factors that allow cells to respond to different stimuli. These regulatory mechanisms help in develo** tissue without affecting ...
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Article
Open AccessIdentification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies
Many studies have been performed to identify various genomic loci and genes associated with the meat quality in pigs. However, the full genetic architecture of the trait still remains unclear in part because o...
