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Article
Open AccessIdentification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies
Many studies have been performed to identify various genomic loci and genes associated with the meat quality in pigs. However, the full genetic architecture of the trait still remains unclear in part because o...
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Article
Open AccessA chromosome-level genome assembly of the Korean crossbred pig Nanchukmacdon (Sus scrofa)
As plentiful high-quality genome assemblies have been accumulated, reference-guided genome assembly can be a good approach to reconstruct a high-quality assembly. Here, we present a chromosome-level genome ass...
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Article
Open AccessComparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig
DNA methylation and demethylation at CpG islands is one of the main regulatory factors that allow cells to respond to different stimuli. These regulatory mechanisms help in develo** tissue without affecting ...
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Article
Open AccessIntegration of multi-omics approaches for functional characterization of muscle related selective sweep genes in Nanchukmacdon
Pig as a food source serves daily dietary demand to a wide population around the world. Preference of meat depends on various factors with muscle play the central role. In this regards, selective breeding able...
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Article
Whole-transcriptome analysis of mouse adipose tissue in response to short-term caloric restriction
Caloric restriction (CR) has been shown to extend the lifespan of many species by improving cellular function and organismal health. Additionally, fat reduction by CR may play an important role in lengthening ...
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Article
Open AccessTwo cases of meningocele and meningoencephalocele in Jeju native pigs
Meningocele and meningoencephalocele of the skull are congenital deformities. Various species, such as pigs, dogs, and cats, are susceptible to congenital meningocele and meningoencephalocele and the incidence...
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Article
Open AccessGenome-wide QTL analysis of meat quality-related traits in a large F2 intercross between Landrace and Korean native pigs
We conducted a genome-wide linkage analysis to identify quantitative trait loci (QTL) that influence meat quality-related traits in a large F2 intercross between Landrace and Korean native pigs. Thirteen meat qua...
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Article
Genome-wide association analysis to identify SNP markers affecting teat numbers in an F2 intercross population between Landrace and Korean native pigs
Most reproductive traits have low heritability and are greatly affected by environmental factors. Teat number and litter size are traits related to the reproduction ability of pigs. To identify quantitative t...
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Article
Comparative transcriptomic analysis to identify differentially expressed genes in fat tissue of adult Berkshire and Jeju Native Pig using RNA-seq
Pork is a major source of animal protein for humans. The subcutaneous, intermuscular and the intramuscular fat are the factors responsible for meat quality. RNA-seq is rapidly adopted for the profiling of the ...
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Article
Association of the gene encoding stearoyl-CoA desaturase (SCD) with fatty acid composition in an intercross population between Landrace and Korean native pigs
Fatty acid (FA) composition is one of the most important parameters for the evaluation of meat quality. The stearoyl-CoA desaturase (SCD) gene is considered a positional candidate gene affecting FA composition...
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Article
A missense mutation (c.1963A<G) of the complementary component 2 (C2) gene is associated with serum Ca++ concentrations in pigs
Serum Ca++ levels play important roles in the humoral immunity. The aim of this study was to detect quantitative trait loci and the associated positional candidate genes affecting baseline serum Ca++ concentratio...
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Article
QTL analysis of back fat thickness and carcass pH in an F2 intercross between Landrace and Korean native pigs
In this study, we conducted a genome-wide linkage analysis to identify the quantitative trait loci (QTL) that influence back fat thickness and carcass pH in an F2 intercross between Landrace and Korean native pig...
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Article
Porcine SPP1 gene polymorphism association with phenotypic traits in the Landrace × Jeju (Korea) black pig F2 population
This study examined polymorphisms of the secreted phosphoprotein 1 (SPP1) gene and its association with growth and carcass traits in the F2 population of the crossbred Landrace × Jeju (Korea) Black pig. The autho...
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Article
A promoter polymorphism of MSTN g.−371T>A and its associations with carcass traits in Korean cattle
A promoter polymorphism of bovine Myostatin (MSTN) gene g.−371T>A was screened in Holstein and two Korean indigenous cattle breeds, Hanwoo and Jeju Black cattle (JBC). The MSTN g.−371T>A polymorphism was found in...
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Article
Characterization of the European type of maternal lineage evident in extant Jeju native pigs
Using a partial D-loop sequence of mtDNA, an intensive analysis was conducted of the maternal lineages of Jeju native pigs (JNPs) from Korea. In total, 100 mtDNA sequences were obtained from Asian wild boars (...
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Article
Characterization of an alternative splicing by a NAGNAG splice acceptor site in the porcine KIT gene
The KIT gene has been shown to have multiple functions in hematopoiesis, melanogenesis, and gametogenesis. In addition, mutations of this gene cause pigmentation disorders in humans and mice and are responsible f...
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Article
Whole-genome association study for the roan coat color in an intercrossed pig population between Landrace and Korean native pig
The roan coat color is characterized by white hairs intermingled with colored hairs. Candidate genes based on comparative phenotypes in horses and cattle involve the KIT and KIT ligand (MGF) genes. Here, we repor...
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Article
Establishment of a resource population of SLA haplotype-defined Korean native pigs
The highly polymorphic porcine major histocompatibility complex (MHC), or the swine leukocyte antigens (SLA), has been repeatedly associated with variations in swine immune response to pathogens and vaccines a...
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Article
Effects of POU1F1 and GH1 genotypes on carcass traits in Hanwoo cattle
Growth hormone and pituitary specific transcription factor-1 are expressed in the pituitary gland and play critical roles in the development and growth of mammals. Genetic polymorphisms of GH1 and POU1F1 genes we...
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Article
Open AccessSINE indel polymorphism of AGL gene and association with growth and carcass traits in Landrace × Jeju black pig F2 population
Genetic polymorphisms in the glycogen debrancher enzyme (AGL) gene were assessed with regard to their association with growth and carcass traits in the F2 population crossbred Landrace and Jeju (Korea) Black pig....
