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Open AccessIdentification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies
Many studies have been performed to identify various genomic loci and genes associated with the meat quality in pigs. However, the full genetic architecture of the trait still remains unclear in part because o...
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Article
Open AccessmsPIPE: a pipeline for the analysis and visualization of whole-genome bisulfite sequencing data
DNA methylation is an important epigenetic modification that is known to regulate gene expression. Whole-genome bisulfite sequencing (WGBS) is a powerful method for studying cytosine methylation in a whole gen...
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Article
Open AccessComparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig
DNA methylation and demethylation at CpG islands is one of the main regulatory factors that allow cells to respond to different stimuli. These regulatory mechanisms help in develo** tissue without affecting ...
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Article
Open AccessPopulation analysis of the Korean native duck using whole-genome sequencing data
Advances in next-generation sequencing technologies have provided an opportunity to perform population-level comparative genomic analysis to discover unique genomic characteristics of domesticated animals. Duc...
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Article
Open AccessTAMA: improved metagenomic sequence classification through meta-analysis
Microorganisms are important occupants of many different environments. Identifying the composition of microbes and estimating their abundance promote understanding of interactions of microbes in environmental ...
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Article
Open AccessGMASS: a novel measure for genome assembly structural similarity
Thanks to the recent advancements in next-generation sequencing (NGS) technologies, large amount of genomic data, which are short DNA sequences known as reads, has been accumulating. Diverse assemblers have be...
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Open AccessmySyntenyPortal: an application package to construct websites for synteny block analysis
Advances in sequencing technologies have facilitated large-scale comparative genomics based on whole genome sequencing. Constructing and investigating conserved genomic regions among multiple species (called s...
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Article
Open AccessTowards realistic benchmarks for multiple alignments of non-coding sequences
With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the most effective tools. Simulation-based bench...