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  1. Article

    Open Access

    Identification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies

    Many studies have been performed to identify various genomic loci and genes associated with the meat quality in pigs. However, the full genetic architecture of the trait still remains unclear in part because o...

    Daehong Kwon, Nayoung Park, Suyeon Wy, Daehwan Lee, Woncheoul Park in BMC Genomics (2024)

  2. Article

    Open Access

    msPIPE: a pipeline for the analysis and visualization of whole-genome bisulfite sequencing data

    DNA methylation is an important epigenetic modification that is known to regulate gene expression. Whole-genome bisulfite sequencing (WGBS) is a powerful method for studying cytosine methylation in a whole gen...

    Heesun Kim, Mikang Sim, Nayoung Park, Kisang Kwon, Junyoung Kim in BMC Bioinformatics (2022)

  3. Article

    Open Access

    Comparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig

    DNA methylation and demethylation at CpG islands is one of the main regulatory factors that allow cells to respond to different stimuli. These regulatory mechanisms help in develo** tissue without affecting ...

    Devender Arora, Jong-Eun Park, Dajeong Lim, Bong-Hwan Choi, In-Cheol Cho in BMC Genomics (2021)

  4. Article

    Open Access

    Population analysis of the Korean native duck using whole-genome sequencing data

    Advances in next-generation sequencing technologies have provided an opportunity to perform population-level comparative genomic analysis to discover unique genomic characteristics of domesticated animals. Duc...

    Daehwan Lee, Jongin Lee, Kang-Neung Heo, Kisang Kwon, Youngbeen Moon in BMC Genomics (2020)

  5. Article

    Open Access

    TAMA: improved metagenomic sequence classification through meta-analysis

    Microorganisms are important occupants of many different environments. Identifying the composition of microbes and estimating their abundance promote understanding of interactions of microbes in environmental ...

    Mikang Sim, Jongin Lee, Daehwan Lee, Daehong Kwon, Jaebum Kim in BMC Bioinformatics (2020)

  6. Article

    Open Access

    GMASS: a novel measure for genome assembly structural similarity

    Thanks to the recent advancements in next-generation sequencing (NGS) technologies, large amount of genomic data, which are short DNA sequences known as reads, has been accumulating. Diverse assemblers have be...

    Daehong Kwon, Jongin Lee, Jaebum Kim in BMC Bioinformatics (2019)

  7. Article

    Open Access

    mySyntenyPortal: an application package to construct websites for synteny block analysis

    Advances in sequencing technologies have facilitated large-scale comparative genomics based on whole genome sequencing. Constructing and investigating conserved genomic regions among multiple species (called s...

    Jongin Lee, Daehwan Lee, Mikang Sim, Daehong Kwon, Juyeon Kim in BMC Bioinformatics (2018)

  8. Article

    Open Access

    Towards realistic benchmarks for multiple alignments of non-coding sequences

    With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the most effective tools. Simulation-based bench...

    Jaebum Kim, Saurabh Sinha in BMC Bioinformatics (2010)