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Article
Treatment failure in intracranial primary germinomas
A radiation dose of 40–50 Gy is able to produce a cure rate of more than 90% in intracranial pure germinoma. However, many attempts have been made to reduce the dose and volume of radiation without compromisin...
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Chapter
The Role of Interleukin-2 in Memory CD8 Cell Differentiation
The current literature on the role of interleukin (IL)-2 in memory CD8+ T-cell differentiation indicates a significant contribution of IL-2 during primary and also secondary expansion of CD8
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Article
Numerical study on spatial distribution of silver nanoparticles inside whole-body type inhalation toxicity chamber
Silver nanoparticles are among the fastest growing product categories in the nanotechnology industry. Several experimental studies reported earlier for its toxicity and its associated risks. Uniform distributi...
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Article
Subacromial im**ement syndrome secondary to scapulothoracic dyskinesia
The authors describe two cases of subacromial im**ement syndrome of the shoulder secondary to scapular dyskinesia caused by a tumor in young adults. The two tumors, an osteochondroma and a ganglion, were loc...
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Article
New surgical algorithm for femoral head split fractures with anatomical study
The femoral head split fracture line is usually located in the anterior–inferior portion of the head. Proper fixation is difficult using the conventional approach without tenotomy, and thus, the authors sought...
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Article
Pit above the lesser tuberosity in axial view radiography
This study examined the relationship between the presence of a pit above the lesser tuberosity on axial view radiographs and rotator cuff tears and compared the demographic data between groups according to the...
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Article
Pattern of care of anaplastic oligodendroglioma and oligoastrocytoma in a Korean population: the Korean radiation oncology group study 13-12
This study investigated the treatment of anaplastic oligodendroglial tumors across nine Korean institutions. We reviewed the medical records from 381 patients with histologically confirmed anaplastic oligodend...
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Article
A multicenter study of anaplastic oligodendroglioma: the Korean Radiation Oncology Group Study 13–12
Although some existing evidence supports the addition of chemotherapy (CT) to radiation therapy (RT) for anaplastic oligodendroglioma treatment, controversy about both the criteria for suitable candidates and ...
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Article
Value of stress ultrasound for the diagnosis of chronic ankle instability compared to manual anterior drawer test, stress radiography, magnetic resonance imaging, and arthroscopy
Clinicians frequently diagnose chronic ankle instability using the manual anterior drawer test and stress radiography. However, both examinations can yield incorrect results and do not reveal the extent of an...
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Article
Open AccessNaïve CD8+ T cell derived tumor-specific cytotoxic effectors as a potential remedy for overcoming TGF-β immunosuppression in the tumor microenvironment
Despite of the potential implications for cancer immunotherapy, conventional approaches using in vitro expanded CD8+ T cells have suboptimal outcomes, mostly due to loss of functionality from cellular exhaustion....
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Article
Open AccessCD45-mediated control of TCR tuning in naïve and memory CD8+ T cells
Continuous contact with self-major histocompatibility complex (MHC) ligands is essential for survival of naïve T cells but not memory cells. This surprising finding implies that T cell subsets may vary in thei...
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Article
Open AccessImpact of Including Peritumoral Edema in Radiotherapy Target Volume on Patterns of Failure in Glioblastoma following Temozolomide-based Chemoradiotherapy
We assessed the impact of including peritumoral edema in radiotherapy volumes on recurrence patterns among glioblastoma multiforme (GBM) patients treated with standard chemoradiotherapy (CRT). We analyzed 167 ...
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Article
Weight-bearing computed tomography findings in varus ankle osteoarthritis: abnormal internal rotation of the talus in the axial plane
To assess the incidence of abnormal internal rotation of the talus in the axial plane in patients with varus ankle osteoarthritis, and to determine whether this incidence differs from the severity of varus ank...
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Article
Role of radiation therapy in primary central nervous system lymphoma
We analyzed patterns of care and outcomes for patients with primary central nervous system lymphoma (PCNSL) in this multi-institutional retrospective study. Between January 2000 and December 2011, 220 patients...
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Article
Mechanically Reinforced Extracellular Matrix Scaffold for Application of Cartilage Tissue Engineering
Scaffolds with cartilage-like environment and suitable physical properties are critical for tissue-engineered cartilage repair. In this study, decellularized porcine cartilage-derived extracellular matrix (ECM...
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Article
Open AccessExtent of resection and molecular pathologic subtype are potent prognostic factors of adult WHO grade II glioma
We evaluated prognostic factors of adult low-grade glioma (LGG) according to the new 2016 WHO classification. Records of 153 patients diagnosed with WHO grade II LGG between 2003 and 2015 were retrospectively ...
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Article
Abdominal obesity increases risk for esophageal cancer: a nationwide population-based cohort study of South Korea
The relationship between overall obesity, as measured by body mass index (BMI) and risk of esophageal squamous cell carcinoma (ESCC) has been reported to show a negative correlation. However, the relationship ...
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Article
Open AccessEfficacy of a high-dose proton pump inhibitor in patients with gastroesophageal reflux disease: a single center, randomized, open-label trial
The extraesophageal manifestations of gastroesophageal reflux disease (GERD) are more difficult to manage than the typical symptoms. The efficacy of high-dose and standard-dose proton pump inhibitors against t...
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Article
Open AccessSelf-reactivity controls functional diversity of naive CD8+ T cells by co-opting tonic type I interferon
The strength of the T cell receptor interaction with self-ligands affects antigen-specific immune responses. However, the precise function and underlying mechanisms are unclear. Here, we demonstrate that naive...
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Article
Open AccessOptimal management of recurrent and metastatic upper tract urothelial carcinoma: Implications of intensity modulated radiation therapy
Upper tract urothelial carcinoma (UTUC) is rare and the treatment for recurrent or metastatic UTUC is unclear. We evaluated the outcomes of salvage and palliative radiotherapy (RT) and prognostic factors in UT...
