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  1. Article

    Open Access

    Naïve CD8+ T cell derived tumor-specific cytotoxic effectors as a potential remedy for overcoming TGF-β immunosuppression in the tumor microenvironment

    Despite of the potential implications for cancer immunotherapy, conventional approaches using in vitro expanded CD8+ T cells have suboptimal outcomes, mostly due to loss of functionality from cellular exhaustion....

    Hong Hanh Nguyen, Therasa Kim, Sang Yun Song, Somang Park in Scientific Reports (2016)