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    Article

    Egr1 regulates regenerative senescence and cardiac repair

    Senescence plays a key role in various physiological and pathological processes. We reported that injury-induced transient senescence correlates with heart regeneration, yet the multi-omics profile and molecul...

    Lingling Zhang, Jacob Elkahal, Tianzhen Wang in Nature Cardiovascular Research (2024)

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    Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury

    Cardiomyocyte proliferation and dedifferentiation have fueled the field of regenerative cardiology in recent years, whereas the reverse process of redifferentiation remains largely unexplored. Redifferentiatio...

    Avraham Shakked, Zachary Petrover, Alla Aharonov in Nature Cardiovascular Research (2023)