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Article
Open AccessPolyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions
Phosphorylation plays a crucial role in the regulation of many fundamental cellular processes. Phosphorylation levels are increased in many cancer cells where they may promote changes in mitochondrial homeosta...
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Protocol
Extracting the Dynamic Motion of Proteins Using Normal Mode Analysis
Normal mode analysis (NMA) is a technique for describing the conformational states accessible to a protein in a minimum energy conformation. NMA gives results similar to those produced by principal components ...
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Article
Open AccessThe role of Lon-mediated proteolysis in the dynamics of mitochondrial nucleic acid-protein complexes
Mitochondrial nucleoids consist of several different groups of proteins, many of which are involved in essential cellular processes such as the replication, repair and transcription of the mitochondrial genome...
