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    Acquired skewing of Lyonization remains stable for a prolonged period in healthy blood donors

    The pattern of X-chromosome inactivation (XCIP), or Lyonization, can be used to distinguish monoclonal from polyclonal cell populations in females. However, a skewed XCIP exists in hematopoietic cells in appro...

    JP van Dijk, L Heuver, E Stevens-Linders, JH Jansen, EJBM Mensink… in Leukemia (2002)