-
Article
Open AccessResults of an early intervention programme for patients with bacteraemia: analysis of prognostic factors and mortality
Bacteraemia is a common cause of morbidity and mortality in patients admitted to hospital. The aim of this study is to analyse the results of a two-year programme for the early optimisation of antibiotic treat...
-
Article
The impact of an antimicrobial stewardship programme on the use of antimicrobials and the evolution of drug resistance
Misuse of antibiotics can provoke increased bacterial resistance. There are no immediate prospects of any new broad-spectrum antibiotics, especially any with activity against enterobacteria, coming onto the ma...
-
Article
Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer
Taxanes and anthracyclines improve the outcome of early breast cancer, although the benefit is limited to a small proportion of patients and are toxic. We prospectively looked for predictors of response to the...
-
Reference Work Entry In depth
Protocols for the Characterization of Solvent Tolerant Microorganisms: Construction and Characterization of Mutants
A number of microorganisms exhibit the unusual property of being tolerant to high concentrations of organic solvents such as toluene, xylenes, ethylbenzene, 1-octanol, 1-decanol, etc. in the culture medium. Th...
-
Article
Open AccessAbacavir/lamivudine has shown similar efficacy to other nucleoside conventional combinations in previously HIV-infected patients: results at 48 weeks
-
Article
Open AccessFactors related to low HDL-cholesterol in HIV-infected patients
-
Article
Primary ovarian trabecular carcinoid tumour: a case report with an immunohistochemical study and a review of the literature
Primary ovarian carcinoid tumours are uncommon neoplasias. There are distinct histological types with different behaviours: insular, trabecular, mucinous and mixed. The trabecular subtype is very rare and unli...
-
Article
Ovarian metastases caused by cholangiocarcinoma: a rare Krükenberg's tumour simulating a primary neoplasm of the ovary: a two-case study
Ovarian metastases represent 10% of all ovarian malignancies. They are characterized by their ability to occasionally reproduce mimicking the clinical and morphological appearance of primary tumours, making di...
-
Chapter
Optical And Electrical Characteristics Of Leds Fabricated From Si-Nanocrystals Embedded In Sio2
Structures containing Si nanocrystals embedded in SiO2 are candidates for optoelectronic and photonic applications due to their intense visible emission at room temperature, high thermal and chemical stability an...
-
Article
FISHing in the microwave: the easy way to preserve proteins. I. Colocalization of DNA probes and surface antigens in human leukocytes
Most of the techniques for simultaneous visualization of proteic cell components and DNA probes are difficult to carry out. We have developed an alternative protocol for simultaneous visualization of DNA probe...
-
Article
Patterns of DNase I sensitivity in the chromosomes of the grasshopperChorthippus parallelus (Orthoptera)
We have analysed the patterns of DNase I/nick translation in the chromosomes of the grasshopperChorthippus parallelus erythropus. Sites of preferential DNase I-nicking were concentrated at the distal chromosome r...
-
Article
Intracranial tuberculosis in AIDS: CT and MRI findings
CT and MRI findings in 35 patients with the acquired immune deficiency syndrome (AIDS) and proven intracranial tuberculosis (TB) are presented. Over 90% of the patients were intravenous drug abusers and in two...
-
Article
Sex chromosome and autosome divergence in Podisma (Orthoptera) in western Europe
-
Article
Restriction endonuclease/nick translation of fixed mouse chromosomes: A study of factors affecting digestion of chromosomal DNA in situ
We used a restriction endonuclease/nick translation procedure to study the ability of certain enzymes, known to cleave mouse satellite DNA in solution, to attack satellite DNA in fixed mouse chromosomes. Altho...
-
Article
Males vs. female meiotic prophase in a grasshopper, Arcyptera microptera (Orthoptera: Acridiae)
Female and male first meiotic prophase are analyzed in the grasshopper Arcyptera microptera with special reference to the heteropycnotic chromatin. Differences in the behaviour of the megameric and X-chromosomes,...
-
Article
Ultrastructural and kinetic studies on uteroglobin secretion in the uterus and oviduct of the pseudopregnant rabbit
The intracellular localization of uteroglobin, a progesterone-induced protein, was studied in uterus and oviduct by means of immunoelectron microscopy with the protein A-gold technique. In the uterus, uteroglo...
-
Article
A model for quantifying genetic recombination in chromosome polymorphisms due to supernumerary heterochromatic segments
Heterochromatic supernumerary segments can modify chiasma distribution in the affected bivalents. A model is developed for quantifying the genetic recombination in populations polymorphic for such segments. Th...
-
Article
Heterochromatin readjusting chiasma distribution in two species of the genus Arcyptera: The effect among individuals and populations
Chiasma variation has been studied in two selected chromosomes from two species of the genus Arcyptera according to the heterochromatin distribution per bivalent.
-
Article
Polyploidization and production of abnormal spermatids inPsophus stridulus (Orthoptera)
Abnormal spermatids exhibiting variation in the number of adjunct centrioles (ACs) (from two to eight) have been analyzed in a spontaneous mutant grasshopper characterized by a high tendency to form polyploid ...
