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Sequential vs myeloablative vs reduced intensity conditioning for patients with myelodysplastic syndromes with an excess of blasts at time of allogeneic haematopoietic cell transplantation: a retrospective study by the chronic malignancies working party of the EBMT
The optimal conditioning for patients with higher risk MDS receiving potentially curative allogeneic haematopoietic stem cell transplant(allo-HCT) remains to be defined. This is particularly the case for patie...
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Article
Der knochenmarktransplantierte Patient auf der Intensivstation
Die allogene hämatopoetische Stammzelltransplantation (HSZT) stellt für viele Patienten mit maligner, aber auch nichtmaligner hämatologischer Grunderkrankung die einzige Chance auf Heilung dar. Dies gilt insbe...
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Article
Post-transplant cyclophosphamide-based haplo-identical transplantation as alternative to matched sibling or unrelated donor transplantation for non-Hodgkin lymphoma: a registry study by the European society for blood and marrow transplantation
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Article
Long-term results of adjuvant donor lymphocyte transfusion in AML after allogeneic stem cell transplantation
Adjuvant transfusion of donor lymphocytes (aDLT) may reduce the risk of relapse after allogeneic stem cell transplantation in high-risk AML. We performed a retrospective analysis on the safety and efficacy of ...
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Article
Hematopoietic stem cell transplantation for T-cell large granular lymphocyte leukemia: a retrospective study of the European Society for Blood and Marrow Transplantation
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Article
Allogeneic hematopoietic cell transplantation as curative therapy for non-transformed follicular lymphomas
Allogeneic hematopoietic cell transplantation (HCT) offers the chance of cure for patients with non-transformed follicular lymphoma (FL), but is associated with the risk of non-relapse mortality (NRM). The aim...
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Article
Second reduced intensity conditioning allogeneic transplant as a rescue strategy for acute leukaemia patients who relapse after an initial RIC allogeneic transplantation: analysis of risk factors and treatment outcomes
Limited therapeutic options are available after relapse of acute leukaemia following first reduced intensity conditioning haematopoietic stem cell transplantation (RIC1). A retrospective study on European Soci...
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Article
Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma
Prognosis is poor for patients with biologically aggressive Non-Hodgkin lymphoma (NHL), refractory to chemotherapy or relapsed after autologous transplantation, especially when no disease control before alloge...
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Article
A survey on unmanipulated haploidentical hematopoietic stem cell transplantation in adults with acute leukemia
The use of unmanipulated graft is increasingly adopted in the setting of allogeneic hematopoietic stem cell transplantation from haploidentical family donors (haplo-SCT) in acute leukemia (AL). We analyzed the...
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Article
Second haematopoietic SCT using HLA-haploidentical donors in patients with relapse of acute leukaemia after a first allogeneic transplantation
Haploidentical haematopoietic SCT (HSCT) using T-cell-replete grafts and post-transplant high-dose CY has found increasing acceptance. Our purpose was to evaluate the feasibility and outcome of this strategy a...
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Article
Open AccessP19. Immunomodulation of blasts in AML-patients (pts) with clinically approved response modifiers to improve anti leukaemic T-cell reactivity: an ex vivo simulation of the clinical situation
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Early allo-SCT for AML with a complex aberrant karyotype—results from a prospective pilot study
In AML, a complex aberrant karyotype is associated with poor response to chemotherapy and dismal prognosis. We prospectively studied the concept of allogeneic haematopoietic SCT (HSCT), performed early and reg...
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Article
Steroidrefraktäre Graft-versus-host-Erkrankung
Eine 42-jährige Frau entwickelt nach der 2. allogenen Stammzelltransplantation bei akuter myeloischer Leukämie eine lebensbedrohliche steroidrefraktäre Graft-versus-host-Erkrankung der Haut mit Blasenbildung, ...
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Article
High antileukemic efficacy of an intermediate intensity conditioning regimen for allogeneic stem cell transplantation in patients with high-risk acute myeloid leukemia in first complete remission
The goal of this analysis was to define the role of the moderate-intensity fludarabin Ara-C amsacrin (FLAMSA)-reduced intensity conditioning (RIC) regimen for patients with high-risk AML undergoing allogeneic ...
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Article
Dose-dependent effects of in vivo antithymocyte globulin during conditioning for allogeneic bone marrow transplantation from unrelated donors in patients with chronic phase CML
We conducted a dose–escalation study with antithymocyte globulin (ATG) in patients undergoing unrelated donor bone marrow transplantation (URD-BMT). This study analyzes the results for 97 patients with chronic...
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47jähriger Patient mit rezidivierenden Lungenembolien bei einer angeborenen Störung des Hämostasesystems
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Pflanzenchemie
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Article
Vergleich des von Altbienen erzeugten Wachses mit „Jungfernwachs“ und gewöhnlichem Bienenwachs
Bienen, die das physiologische Baualter überschritten haben, wurden zu neuerlicher Wachsbildung veranlaßt. Wie aus den ermittelten Kennzahlen hervorgeht, unterscheidet sich dieses Altbienenwachs nicht wesentli...
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Pflanzenphysiologisch-chemische und agrikulturchemische Mikromethoden
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Bestimmung der Mineralstoffe in Pflanzen