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  1. Article

    Open Access

    Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade

    Tumor-infiltrating lymphocytes (TILs) have been associated with outcomes in HER2-positive breast cancer patients treated with neoadjuvant chemotherapy and trastuzumab. However, it remains unclear if TILs could...

    M. C. Liefaard, A. van der Voort, M. van Seijen, B. Thijssen… in npj Breast Cancer (2024)

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  2. No Access

    Article

    Targeting the RB-E2F pathway in breast cancer

    Mutations of the retinoblastoma tumor-suppressor gene (RB1) or components regulating the CDK-RB-E2F pathway have been identified in nearly every human malignancy. Re-establishing cell cycle control through cyclin...

    J Johnson, B Thijssen, U McDermott, M Garnett, L F A Wessels, R Bernards in Oncogene (2016)

  3. Article

    Open Access

    A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer

    To explore the parmacokinetics, safety and tolerability of paclitaxel after oral administration of SMEOF#3, a novel Self-Microemulsifying Oily Formulation, in combination with cyclosporin A (CsA) in patients w...

    S A Veltkamp, B Thijssen, J S Garrigue, G Lambert, F Lallemand… in British Journal of Cancer (2006)

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