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Article
Open AccessPreferences for colorectal cancer screening strategies: a discrete choice experiment
Guidelines underline the role of individual preferences in the selection of a screening test, as insufficient evidence is available to recommend one screening test over another. We conducted a study to determi...
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Article
Open AccessThe impact of healthcare costs in the last year of life and in all life years gained on the cost-effectiveness of cancer screening
It is under debate whether healthcare costs related to death and in life years gained (LysG) due to life saving interventions should be included in economic evaluations. We estimated the impact of including th...
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Article
Open AccessScreening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels
Immunochemical faecal occult blood testing (FIT) provides quantitative test results, which allows optimisation of the cut-off value for follow-up colonoscopy. We conducted a randomised population-based trial t...
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Article
The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis
The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-spar...
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Article
Use of Stimulated Serum Estradiol Measurements for the Prediction of Hyperresponse to Ovarian Stimulation in in Vitro Fertilization (IVF)
Purpose: In ovarian stimulation an exaggerated ovarian response is often seen and is related to medical complications, such as ovarian hyperstimulation syndrome (OHSS), and increased patient discomfort. If it we...
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Article
Open AccessSurvival of patients with nonseminomatous germ cell cancer: a review of the IGCC classification by Cox regression and recursive partitioning
The International Germ Cell Consensus (IGCC) classification identifies good, intermediate and poor prognosis groups among patients with metastatic nonseminomatous germ cell tumours (NSGCT). It uses the risk fa...
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Article
Which patients with hypertension and atherosclerotic renal artery stenosis benefit from immediate intervention?
The objective was to identify subgroups of patients with hypertension and atherosclerotic renal artery stenosis who may benefit from immediate intervention. In the DRASTIC study, patients with hypertension, si...
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Article
Open AccessExtended duration of the detectable stage by adding HPV test in cervical cancer screening
The human papillomavirus test (HPV) test could improve the (cost−) effectiveness of cervical screening by selecting women with a very low risk for cervical cancer during a long period. An analysis of a longitu...
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Article
Open AccessLow risk of cervical cancer during a long period after negative screening in the Netherlands
A condition for effective cervical cancer screening is a low incidence of cervical cancer after negative screening compared to that in the absence of screening. This relative risk was studied for the period 19...
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Article
Open AccessExternal validity of a prediction rule for residual mass histology in testicular cancer: an evaluation for good prognosis patients
We assessed the external validity of a prediction rule for nonseminomatous testicular cancer patients. The rule was developed to predict the probability of retroperitoneal metastases being benign (only necrosi...
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Chapter and Conference Paper
How Valid Is a Prediction Rule for Residual Retroperitoneal Mass Histology in NSGCT?
A prediction rule is available to predict the histology of residual retroperitoneal masses in patients treated with chemotherapy for metastatic nonseminomatous germ cell tumours [1]. The rule provides the prob...
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Article
Spinal cord stimulation in patients with critical limb ischemia: A preliminary evaluation of a multicentre trial
Background: Spinal cord stimulation (SCS) is known to reduce chronic pain. The technique was offered to patients with critical limb ischemia due to atherosclerosis, in which vascular reco...
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Article
Acoustic detection of intracranial aneurysms: A decision analysis
We present a further evaluation of an improved recording method for the acoustic detection of intracranial aneurysms (ADA). A sensor was applied to the patient's eyes. Two measures were derived to summarize th...
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Chapter and Conference Paper
ESES-trial: Evaluation of epidural spinal cord electrical stimulation (ESES) in critical limb ischemia — a randomized controlled clinical trial
Peripheral arterial disease due to atherosclerosis is a common disease, particularly among the elderly. The prevalence of symptoms of intermittent claudication was reported to be 0.2–1.9% for men below 50 year...
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Article
Unruptured intracranial arteriovenous malformations with hereditary haemorrhagic telangiectasia
Clinical decision analysis is applied to treatment decisions for three patients with unruptured familial intracranial arteriovenous malformations (AVMs) in association with hereditary haemorrhagic telangiectas...
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Chapter and Conference Paper
Cost-Effectiveness Analysis of Breast Cancer Screening
There are 3 related types of analysis for assessing relationships between costs, risks and health benefits [1, 2], the first one being the cost-effectiveness analysis (CE-analysis). In this case, one effect me...
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Chapter
Prognosis and Prediction of Outcome in Comatose Head Injured Patients
Recent studies on the prognosis of comatose head injured patients have identified single powerful prognostic features at various time points during the first month after onset of coma. Using appropriate statis...
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Chapter and Conference Paper
Mathematical Modelling of Interacting Factors in the Analysis and Optimization of Cancer Screening
The results and effects of screening are determined by a large number of factors, and by the complex interactions between these factors. No direct observation is possible of factors with a great impact on effe...
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Chapter and Conference Paper
The Impact of Therapeutic Improvements on the Value of Mass Screening for Early Detection of Disease: The Case of Cervical Cancer
The problem under study is the impact of survival-improvement on the value of mass-screening for early detection of disease. Two kinds of survival-improvement are defined: decrease in case-fatality, and increa...
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Chapter and Conference Paper
Decision Making on Mass Screening for Disease II. Sensitivity of Results to Changes in Model Assumptions
A simulation program has been used in order to predict the effects of mass screening for cervical cancer in the Netherlands. The reliability of these predictions depends on the knowledge of the natural history...
