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Article
Open Access‘Value-based methodology for person-centred, integrated care supported by Information and Communication Technologies’ (ValueCare) for older people in Europe: study protocol for a pre-post controlled trial
Older people receive care from multiple providers which often results in a lack of coordination. The Information and Communication Technology (ICT) enabled value-based methodology for integrated care (ValueCar...
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Article
Open AccessFollow-up infarct volume as a mediator of endovascular treatment effect on functional outcome in ischaemic stroke
The putative mechanism for the favourable effect of endovascular treatment (EVT) on functional outcome after acute ischaemic stroke is preventing follow-up infarct volume (FIV) progression. We aimed to assess ...
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Article
Impaired fasting glucose is associated with unfavorable outcome in ischemic stroke patients treated with intravenous alteplase
Hyperglycemia on admission and diabetes mellitus type II are associated with unfavorable outcome in stroke patients. We studied whether impaired fasting glucose (IFG) is associated with unfavorable outcome in ...
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Chapter and Conference Paper
The Effect of Non-contrast CT Slice Thickness on Thrombus Density and Perviousness Assessment
[Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of sl...
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Article
Open AccessThe ThRombolysis in UnconTrolled Hypertension (TRUTH) protocol: an observational study on treatment strategy of elevated blood pressure in stroke patients eligible for IVT
Intravenous thrombolysis (IVT) with (recombinant) tissue plasminogen activator is an effective treatment in acute ischemic stroke. However, IVT is contraindicated when blood pressure is above 185/110 mmHg, bec...
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Article
Ambivalence among neurologists and neurosurgeons on the treatment of chronic subdural hematoma: a national survey
No class I evidence exists about the optimal treatment of chronic subdural hematoma (CSDH). The aim of this study was to evaluate current practice of CSDH patients with different neurological grades, and proba...
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Article
Open AccessC-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death
Acute ischemic stroke may trigger an inflammatory response that leads to increased levels of C-reactive protein (CRP). High levels of CRP may be associated with poor outcome because they reflect either an infl...
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Article
Open AccessAtherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors
The purpose of this study was to examine the volume and the composition of atherosclerotic plaque in symptomatic carotid arteries and to investigate the relationship between these plaque features and the sever...
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Article
Accuracy of CT angiography in the assessment of a fetal origin of the posterior cerebral artery
An uncommon cause of cerebral ischemia in the territory of the posterior cerebral artery (PCA) is the combination of a fetal origin of the PCA and atherosclerotic disease in the internal carotid artery. This s...
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Article
The validity and reliability of signs of early infarction on CT in acute ischaemic stroke
It has been suggested that subtle signs of early cerebral infarction on CT are important indicators of outcome and of the effect of thrombolytic treatment in acute ischaemic stroke. We studied these signs pro...
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Article
The diagnostic value of colour duplex ultrasound for symptomatic carotid stenosis in clinical practice
We assessed the accuracy of colour duplex ultrasound for the detection of severe (70–99 %) symptomatic carotid stenosis in a clinical setting, in order to assess whether it could make carotid angiography unne...
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Article
Coagulation disorders in young adults with acute cerebral ischaemia
We analysed the results of coagulation studies in an unselected series of young adults with acute cerebral ischaemia. Our aims were (a) to determine the prevalence of coagulation disorders among these patient...
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Article
Acoustic detection of intracranial aneurysms: A decision analysis
We present a further evaluation of an improved recording method for the acoustic detection of intracranial aneurysms (ADA). A sensor was applied to the patient's eyes. Two measures were derived to summarize th...
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Article
Unruptured intracranial arteriovenous malformations with hereditary haemorrhagic telangiectasia
Clinical decision analysis is applied to treatment decisions for three patients with unruptured familial intracranial arteriovenous malformations (AVMs) in association with hereditary haemorrhagic telangiectas...
