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Article
Open AccessThe impact of antibiotic stewardship interventions and patient related factors on antibiotic prescribing in a vascular surgical department
The development of guidelines tailored to the departments’ needs and counselling during ward rounds are important antibiotic stewardship (AS) strategies. The aim was to analyse the impact of AS ward rounds and...
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Article
Letter of response to: spheno-orbital meningiomas
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Article
A single centre’s experience of managing spheno-orbital meningiomas: lessons for recurrent tumour surgery
Spheno-orbital meningiomas are complex tumours involving the sphenoid wing and orbit. Various surgical strategies are available but treatment remains challenging and patients often require more than one surgic...
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Article
C-reactive protein binds to integrin α2 and Fcγ receptor I, leading to breast cell adhesion and breast cancer progression
C-reactive protein (CRP) is an acute phase protein synthesized upon the inflammatory responses, associated with breast cancer. The process of tumor cell invasion and metastasis involves the adherence of cells ...
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Article
Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers
There are currently no effective targeted therapies for KRAS mutant cancers. Therapeutic strategies that combine MEK inhibitors with agents that target apoptotic pathways may be a promising therapeutic approach. ...
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Article
Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression
A crucial role of the inflammatory lipid sphingosine-1-phosphate (S1P) in breast cancer aggressiveness has been reported. Recent clinical studies have suggested that C-reactive protein (CRP) has a role in brea...
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Article
Vitamin B and C levels of homeless patients who visit the emergency department with alcohol ingestion
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Article
Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src
Translationally controlled tumor protein (TCTP) is implicated in cell growth and malignant transformation. TCTP has been found to interact directly with the third cytoplasmic domain of the α subunit of Na,K-AT...
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Article
Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension
In this study, we determined the association of 1180 non-synonymous single-nucleotide polymorphisms (SNPs) with systolic blood pressure (SBP) and hypertensive status. A total of 8842 subjects were taken from t...
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Article
Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study
Anterior cervical discectomy and fusion (ACDF) may be considered to be the gold standard for treatment of symptomatic degenerative disc disease within the cervical spine. However, fusion of the segment may res...
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Article
Serial changes in ICU-acquired pneumonia pathogen after the remodeling of the environment in a MICU
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Article
Establishment of a follicular lymphoma cell line (FLK-1) dependent on follicular dendritic cell-like cell line HK
A novel cell line, FLK-1, was established from bone marrow cells of a patient with follicular lymphoma by means of co-culture with follicular dendritic cell (FDC)-like cell line HK. Immunophenotypic analysis s...
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Chapter and Conference Paper
Two Highly Polymorphic VNTR Loci D5S110 (LH1) and D4S139 (Ph30): Analysis, Formal and Population Genetic Data
The experimental technique is described that enable RFLP ty** with the two hypervariable VNTR loci D5S110 (LH1) and D4S139 (pH30). Population and formal genetic studies were performed using Haelll restricted...
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Article
PCR-based ty** of DNA extracted from cigarette butts
Limited genetic marker information can be obtained from saliva by ty** by conventional serological means. Thus, the application of PCR-based DNA ty** methods was investigated as a potential approach for ty...
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Chapter
Possibilities for Optimalization of Plant Nutrition by New Agrochemical Substances--Especially in Cereals
When discussing measures for further increasing crop production by optimalizing plant nutrition, it is natural to start by asking to what extent the productivity of crop plants can be increased under specific ...
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Book and Conference Proceedings