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  1. No Access

    Article

    Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers

    There are currently no effective targeted therapies for KRAS mutant cancers. Therapeutic strategies that combine MEK inhibitors with agents that target apoptotic pathways may be a promising therapeutic approach. ...

    A N Hata, S Rowley, H L Archibald, M Gomez-Caraballo, F M Siddiqui, F Ji… in Oncogene (2017)

  2. Article

    Open Access

    Impact of adolescent ethanol exposure and adult amphetamine self-administration on evoked striatal dopamine release in male rats

    Adolescent binge drinking is common and associated with increased risk of substance use disorders. Transition from recreational to habitual ethanol consumption involves alterations in dorsal striatal function,...

    L. Granholm, S. Rowley, M. Ellgren, L. Segerström, I. Nylander in Psychopharmacology (2015)

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  3. No Access

    Article

    Complementary medicine use in patients with head and neck cancer in Ireland

    The objectives of the study were: first, to determine the prevalence of traditional medicine (TM) and complementary and alternative medicine (CAM) use in head and neck cancer patients in Ireland; second, to ed...

    Mohamed Amin, F. Glynn, S. Rowley, G. O’Leary… in European Archives of Oto-Rhino-Laryngology (2010)

  4. No Access

    Article

    Barriers to mental health service use among hematopoietic SCT survivors

    This study examined barriers to mental health service use and the demographic, medical and psychosocial correlates of these barriers among hematopoietic SCT (HSCT) survivors. A sample of 253 HSCT survivors who...

    C E Mosher, K N DuHamel, C M Rini, Y Li, L Isola, L Labay… in Bone Marrow Transplantation (2010)

  5. No Access

    Article

    Management of gastrointestinal stromal tumours: a single-centre experience

    Gastrointestinal stromal tumours (GISTs), although rare, are increasingly recognized, characterized immuno-phenotypically in most cases by a mutation in C-Kit. The advent of imatinib, a tyrosine kinase inhibit...

    J. Butt, S. Rowley, P. J. Byrne, J. V. Reynolds in Irish Journal of Medical Science (2007)

  6. No Access

    Article

    A prospective study of quality of life following multimodal treatment and oesophagectomy versus oesophagectomy alone

    R. McLaughlin, J. A. McCullough, J. Moore, S. Rowley… in Irish Journal of Medical Science (2002)

  7. Article

    Sinonasal melanoma: An unusual cause of proptosis

    L Bender, S Rowley in Eye (1999)

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  8. No Access

    Article

    High-dose busulfan, melphalan and thiotepa followed by autologous peripheral blood stem cell (PBSC) rescue in patients with advanced stage III/IV ovarian cancer

    The purpose of this study was to evaluate the efficacy of high-dose chemotherapy (HDC) with busulfan, melphalan and thiotepa (BUMELTT) followed by autologous PBSC infusion in treating patients with advanced ov...

    LA Holmberg, T Demirer, S Rowley, CD Buckner, G Goodman… in Bone Marrow Transplantation (1998)

  9. No Access

    Article

    High-dose busulfan, melphalan, thiotepa and peripheral blood stem cell infusion for the treatment of metastatic breast cancer

    The purpose of this study was to determine the outcome of patients with metastatic breast cancer treated with high-dose busulfan (Bu), melphalan (Mel) and thiotepa (TT) followed by peripheral blood stem cell (...

    WI Bensinger, KS Schiffman, L Holmberg, FR Appelbaum… in Bone Marrow Transplantation (1997)

  10. No Access

    Article

    American Society of Colon and Rectal Surgeons 95th Annual Convention Podium and Poster Abstracts June 9–14, 1996 Seattle, Washington

    D. Obrand, P. H. Gordon, S. Rowley, R. H. Grace, S. Rai… in Diseases of the Colon & Rectum (1996)

  11. No Access

    Chapter and Conference Paper

    Klonierung und Expression von Cytosin Deaminase — Ansätze für eine in situ Chemotherapie des kolorektalen Karzinoms

    Das kolorektale Karzinom ist das zweithäufigste Karzinom in Europa und den USA. Trotz Fortschritten in Diagnostik und Therapie hat sich die Prognose dieser Erkrankung in den vergangegen 15 Jahren nicht wesentl...

    M. Lindauer, S. Rowley, J. Gebert, Ch. Herfarth, H. K. Schackert in Chirurgisches Forum ’94 (1994)

  12. No Access

    Chapter and Conference Paper

    Modification of DNA Ploidy in Rectal Cancer Following Pre-Operative Radiotherapy

    Recent studies on colorectal cancer [1–6] and on rectal cancer alone [7–10] using flow cytometry analysis have demonstrated the prognostic role of DNA stemline assessment. Selected patients who underwent a cur...

    M. J. C. Matter, S. Rowley, G. D. Oates in Updates in Colo-Proctology (1992)

  13. No Access

    Article

    Reduced tumour growth of the human colonic cancer cell lines COLO-320 and HT-29 in vivo by dietary n-3 lipids

    Seventy-five nude mice received subcutaneous inoculation with 1 X 10(7) cells of the human colonic cancer cell lines COLO-320 or HT-29. Tumour growth was assessed over 4 weeks in animals given one of three iso...

    M Sakaguchi, S Rowley, N Kane, C Imray, A Davies, C Jones… in British Journal of Cancer (1990)

  14. No Access

    Article

    Abstracts

    L. Rosen, J. Reed, D. Ufberg, H. Thorburn, K. Carter… in Diseases of the Colon & Rectum (1990)